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Resistance to Covid-19: British Survey


Women in protective masks are passing through Brixton Market in southern London as the UK continues to block the spread of coronaviruses.

Victoria Jones | PA Image Via Getty Images

Resistance to Covid-19 may last only a few months, according to a UK study that questioned the longevity of a possible coronavirus vaccine.

Researchers at King’s College London may find that antibody responses to coronavirus peak at 3 weeks after the first onset of symptoms, but begin to decline after only a few months.

the study, Published on preprint server MedRxiv on Saturday, not yet peer reviewedFrom March to June, the NHS Foundation Trust in Guy’s and St. Thomas, which operates multiple hospitals in London, examined antibody levels in 64 virus-positive patients and 6 healthcare workers. We also monitored 31 staff members who volunteered for regular antibody testing.

The researchers found that the levels of antibodies able to fight coronavirus peaked three weeks after the onset of symptoms, but then decreased. Sixty percent of the people tested in the study had “strong” levels of the antibody on average 23 days after the first onset of symptoms, 65 days after the first signs of symptoms, but only 16.7% of those tested “This is a strong antibody level.

For unknown reasons, patients with more serious illness had higher antibody levels, KCL mentioned, And some individuals who developed the antibody were asymptomatic.

Researchers show that antibody responses to Covid-19 are similar to other human coronaviruses that are prone to individual antibody responses, including seasonal coronaviruses associated with SARS and colds He says the study has confirmed that. Only 12 weeks to 12 to 34 months after infection, it gets worse over time. “

This research was led by Dr. Katie Doores, Department of Immunology and Microbiology, KCL. The study states that antibody responses to circulating SARS-CoV-2 (or “severe acute respiratory syndrome coronavirus 2” (a virus that causes Covid-19 disease) are reduced after infection, and Research is needed to determine the level of antibody required for protection.

“We need to continue to measure antibody responses in these individuals to see if the antibody titers continue to decline or if there is a plateau at steady state,” she said. Antibody titer refers to the presence and amount of Antibodies in human blood.

The study raises questions about how well people infected with coronavirus are protected from subsequent reinfection, and the durability of potential vaccines...

World Health Organization official said Monday Patients recovering from Covid-19 may be infected with coronavirus againCiting a similar study, suggesting that immunity may decline after a few months.

Dr. Maria Van Kerkhove, head of the WHO Emerging Diseases division, said the patient “has some immune response.”

In a press conference at the organization’s Geneva headquarters, she added, “What we don’t know is how strong that protection is and how long it lasts.”

“There are, therefore, many studies underway that try to answer these questions,” she said.

Meanwhile, a peer-reviewed study published last week in Lancet’s Medical Journal showed that Covid-19 antibodies in the Spanish population “It was not enough to provide herd immunity.” This is when a population is allowed some exposure to the virus in order to build immunity among the general population.


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