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CVD Risk in Epilepsy Increases Dementia Risk, Teriflunomide in RIS, FDA Approves Dry Sensor EEG Headset
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Welcome to a special edition of the Neurology News Network. My name is Marco Merio.
A cross-sectional study of approximately 500,000 people with epilepsy, stroke, or migraine found that focal epilepsy was associated with symptoms such as: Greatest risk of developing dementia, increased significantly in those at high cardiovascular risk. Using data collected from the UK Biobank, 3,864 were diagnosed with focal epilepsy only, 6,397 had a history of stroke only, and 14,158 had migraine only. Patients were followed for more than 10 years, and those with focal epilepsy were at increased risk of developing dementia compared with those with stroke or migraine. Among high cardiovascular risk individuals with focal epilepsy (n = 762), 9.1% developed dementia compared to only 0.4% of low cardiovascular risk controls. When only individuals at high cardiovascular risk were compared, patients with focal epilepsy had a HR for developing dementia of 3.73 compared with controls, whereas stroke patients had a HR of 1.90 compared with controls. .
Phase 3 TERIS Trial Results found that treatment with teriflunomide (Aubagio, Sanofi) significantly shortened the time to first clinical event in patients with radioisolation syndrome (RIS), which is considered a presymptomatic stage of multiple sclerosis (MS). showed. Introduced in 2009, RIS refers to the disease in which white matter lesions that meet the criteria for MS occur in individuals with no history of clinical demyelinating attacks or another etiology. Some argue that RIS is not a true clinical diagnosis, but part of a continuum from healthy to sick that is indistinguishable on the basis of imaging and clinical features. Twenty-eight clinical events were detected during follow-up, 20 in the placebo group and 8 in the teriflunomide group. The adjusted model results further demonstrated the superiority of teriflunomide in preventing first clinical events.
The FDA granted the novel 510(k) clearance, according to a Cumulus Neuroscience announcement. dry sensor EEG headsetis a user-friendly device that enables self-directed use and produces clinical-grade data for remote physician review. Cumulus EEG devices are designed for both adult and adolescent patients, come in four sizes and are easy to put on by yourself in less than five minutes following the guidance of Cumulus Mobile his app, making them ideal for EEG technicians and medical professionals alike. No need for home support. The platform combines clinical-grade home-based data with machine learning analytics and a large real-world database of annotated long-term concordant data. “By providing reliable data across multiple areas of brain function, from specific disease symptoms to functional neurophysiology, we can Clinical researchers can accelerate the development of treatments for neuropsychiatric and neurodegenerative diseases.” – Bringing hope to millions of patients and families overcoming unmet needs in the CNS ecosystem. ”
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