Health
Researchers say there is no evidence to support the spread of coronaviruses from dogs to humans
An image to represent. (AP)
They said the study published earlier this year, alleging that the coronavirus might have jumped from dogs to humans, was scientifically flawed and did not provide direct evidence to support its conclusions.
- IANS
- Last update: 16:52 July 15, 2020
A study published earlier this year alleging that the coronavirus (Covid-19) might have jumped from dogs to humans was scientifically flawed and said it did not provide direct evidence to support its conclusions. Say.
“During this Covid-19 period, we’ve seen people make big leapfrogging conclusions that aren’t justified by evidence, and this seems to be one of them.”
In a current study published in the Journal of Molecular Biology and Evolution, the research team viewed an April 2020 study by Xuhua Xia of the University of Ottawa, Canada. This suggests that stray dogs may be the cause of a pandemic.
Many scientists are interested in the origin of the new coronavirus. They want to know which host the SARS-CoV-2 virus responsible for Covid-19 came from before jumping from animal to human.
According to researchers, the classic way to deal with this is to find viruses with similar genomic sequences in a particular animal host.
Focusing on the function of the coronavirus genome, known as CpG content, Xia discovered that a closely related canine coronavirus has CpG content similar to SARS-CoV-2.
Because this distant virus replicated well in the canine gastrointestinal tract, he concluded that the canine intestine was the ideal place to influence the CpG content of ancestral SARS-CoV-2.
“However, given that all mammals have a digestive tract, there is no evidence of a logical premise for the summer debate,” the researchers wrote.
They showed that dogs were not specific in their content of ZAP and ABOBEC3G proteins.
“In addition, a recent inoculation study showed that other domesticated mammalian hosts were very sensitive to SARS-CoV-2, but dogs showed low susceptibility, and traces of viral RNA were detected in any dog organ. It wasn’t,” the scientist wrote.
According to the current research team, the recent origin of SARS-CoV-2 is unknown, but the best current evidence is that the bat bat and possibly a Chinese spiny anteater could be passed on to humans. There is.
There is recent strong evidence that the virus has jumped between humans and these animals or other intermediate hosts.
Bat and pangolin viruses also have CpG content similar to human SARS-CoV-2, so the environment that affected the viral CpG was long ago, probably one of these two mammals. It must have happened one time, the authors say.
The researchers concluded that the proposition that dogs are likely to be the recent ancestors of SARS-CoV-2 is not justified by available evidence.
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