Health
RECOVER study expands valid definition of long-term novel coronavirus
a Research Led by the National Institutes of Health recovery initiative With the support of NYU Langone Health, home of the Clinical Science Core (CSC) for this effort, we are providing an extended and actionable definition of novel coronavirus over time.
“This study is an important step towards defining long-term novel coronavirus beyond individual symptoms,” said the study authors. Leora Horwitz, M.D.director of Healthcare Innovation and Delivery Science Center He is also a Co-Principal Investigator of the RECOVER CSC at New York University Langone. “While this definition may evolve over time, it will serve as an important foundation for scientific discovery and treatment design.”
The study, which included RECOVER investigators nationwide, established a symptom-based scoring system that most clearly distinguishes between previously infected patients and those who have not previously reported infection. Researchers used these symptoms to identify patients with long-standing COVID-19. The results, according to the authors, are based on a survey of self-reported symptoms in 9,764 patients and will be validated in the future. Findings are then compared to clinical examination and imaging.
As of May 2023, more than 100 million Americans have been infected with SARS-CoV-2, the virus that causes COVID-19, and experts estimate that about It is said to reach 100 million people. 6 percent Some people infected with the virus continue to experience a number of symptoms collectively referred to as “long-lasting novel coronavirus.” More than 200 symptoms that affect every organ system of the body are associated with post-COVID-19 conditions.
It was published online on May 25th. Journal of the American Medical Association, The study investigated 37 conditions across multiple areas and organs of the body. The researchers applied statistical analysis to identify 12 symptoms that best differentiated those with long-term COVID-19 from those without. These include post-exercise fatigue, fatigue, foggy head, dizziness, gastrointestinal symptoms, heart palpitations, libido and performance problems, loss of smell and taste, thirst, chronic cough, chest pain, and abnormal movements.
By assigning points to each of 12 symptoms, the team gave each participant a score based on a combination of symptoms, and found that 23 percent of participants who had previously had COVID-19 had It turned out that the research threshold for long-term novel coronavirus infection was exceeded. Researchers who obtained these scores found that certain symptoms occurred at higher rates in certain patient groups, and based on these symptom patterns he defined four clusters.
“Now that we are able to identify long-term COVID-19 patients, we are able to initiate more in-depth studies to understand its mechanisms,” said corresponding author, RECOVER Data Resource Core (DRC ), said Dr. Andrea Fawkes, principal investigator of , Professor of Medicine, Harvard Medical School, and Director of Biostatistics, Massachusetts General Hospital. “These findings set the stage for identifying effective therapeutic strategies for long-term COVID-19 patients, and understanding the biological underpinnings will be critical to that effort. ”
RECOVER—studying COVID-19 to enhance recovery—why some people develop long-lasting symptoms after COVID-19 and how to detect, treat, and prevent COVID-19 in the long run. It is a nationwide effort dedicated to understanding. As his CSC, New York University Langone is responsible for integrating the research activities of nearly 200 clinical sites nationwide.
complex illness
The study also found that long-lasting COVID-19 was more common and severe in study participants infected or unvaccinated before the emergence of the Omicron strain in late 2021. . In addition, reinfection was also associated with increased frequency and severity of COVID-19 over time.
By introducing a 12-symptom scoring system, researchers were able to identify four subgroups of patients with different symptom clusters. Some of these clusters span multiple body systems, suggesting that some people with prolonged COVID-19 infection may have a systemic reaction to the virus. Suggested.
The ongoing research being conducted by RECOVER will serve as the basis for a planned clinical trial whose interventions, including brain fog and nerve injury, also known as autonomic dysfunction, are outlined in this study. It is rooted in many of the symptoms. The RECOVER clinical trial is expected to begin enrolling patients in 2023.
The study’s writing committee included Dr. Horwitz and Dr. Fawkes, as well as lead author Dr. Thanayott Taweetai of Massachusetts General Hospital and Harvard Medical School. Additional authors are her Caitlin Selvaggi, MS, Daniel Shinnick, MS, and Carolin Schulte, PhD, from Massachusetts General Hospital. Elizabeth Carlson, M.D., M.D., Bruce Levy, M.D., Rachel Atchley, M.D., Brigham and Women’s Hospital. Cyram Parthasarathy, M.D., University of Arizona Tucson School of Medicine. Updar Singh, M.D., Stanford University School of Medicine. Sarah Jolly, M.D., University of Colorado Anschutz Medical Campus. Tiffany Walker, M.D., Emory University. Dr. Emily Levitan of the University of Alabama at Birmingham. Lisa McCorkell, Member of Congress for the Patient-Driven Research Community. Grace McCombie, M.D., Case Western Reserve University. and Dr. Girish Nadkarni of Icahn School of Medicine, Mount Sinai.
This study was funded by NIH agreements OT2HL161841, OT2HL161847, and OT2HL156812. For more information, recovery initiative. In addition to Dr. Horwitz, his CSC at New York University Langone is co-led by his RECOVER Co-Principal Investigator. Stuart D. Katz, M.D.Founding Director of the Heart Failure Program at New York University Langone, and Helen L. Kimmel and Martin S. Kimmel Professors of Advanced Cardiac Therapeutics, New York University. Faculty of Medicine, Andrea B. Troxell, ScDdirector of Department of Biostatistics and professor Department of Population and Healthand Rachel S. Gross, MDDirector of Pediatric Research and Assistant Professor at RECOVER CSC Pediatrics at New York University Grossman School of Medicine.
media inquiries
Greg Williams
Phone: 212-404-3500
[email protected]
Domonique Chaplin
Recover NYU Langone Health’s Clinical Science Core
[email protected]
Sources 2/ https://nyulangone.org/news/recover-study-offers-expanded-working-definition-long-covid The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]