Connect with us

Health

Researchers suggest that nasal coronavirus vaccine is more effective than injected

 


Key Point

  • Intranasal vaccination can attack the virus, one of the important entrances to the human body-the mucous membrane overlying the upper respiratory system.
  • Nasal vaccination also causes mucosal protection at the site of infection
  • Intranasal vaccination may confer protection against mutant strains

Intranasal vaccination is rare. However, the benefits, especially for highly infectious diseases such as COVID-19, may be more effective than traditional intramuscular injection.

That’s because intranasal vaccination, given as an infusion or fine spray, can directly attack COVID-19, one of the key points where the virus enters the human body-the mucous membrane, or the mucosal system of the nose and upper respiratory tract. The mucous membrane is a membrane that covers various cavities of the human body and covers the surface of internal organs.

On the other hand, injecting the new COVID-19 vaccine into the mucosa-free upper arm may not be the most effective option.

Many doctors also make sense to develop a mucosal vaccine for the respiratory tract given the potency and rapid spread of the virus that causes COVID-19. SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) is the virus that causes COVID-19.

The main advantage For nasal vaccination, the nasal cavity is easily accessible. Nasal vaccination also elicits both mucosal protection at the site of infection and a systemic immune response, or antibody formation. On the other hand, intramuscular vaccination of the arm mainly induces a systemic immune response.

A successful nasal vaccine is FluMist Quadrivalent, a “live attenuated influenza vaccine” introduced in 2003. This nasal spray vaccine contains the attenuated influenza virus and has been shown to be more effective than influenza vaccination among young children.

“I know how strong a mucosal reaction is to a viral pathogen, so it’s ideal to think about a mucosal vaccine.” Dr. Akiko Iwasaki, An immunologist at Yale University.

Her observations were seconded by Dr. Avery August, an immunologist at Cornell University. “It’s less than ideal when it breaks down and presents pathogens in a way that the immune system can’t naturally see them,” Dr. August said. “You risk not producing the correct immune response.”

This is an established fact that the mucous membranes are very immune-competent. In the development of other viruses, even small amounts of antigen have been shown to elicit protective responses in the mucosa.

This is why some doctors argue that intranasal vaccination may provide protection against infections at other mucosal sites such as the lungs, intestines, and genital tract. Intranasal vaccination may also confer cross protection against mutant strains through mucosal antibody secretion.

In agreement with the efficacy of nasal vaccination, several research groups around the world are working on nasal coronavirus vaccines. Meanwhile, many companies, including Baxart, an American biotechnology company, are developing alternatives. This option is an oral formulation that delivers the drug to another mucosa, the cavernous mucosa of the intestine.

Two Leading Coronavirus Vaccine Project Leaders-University of Oxford, Alliance with AstraZeneca Institute, and Sinovac of China-To Conduct Clinical Trials in Brazil Two Leading Coronavirus Vaccine Project Leaders-University of Oxford, Alliance with AstraZeneca Institute, and Sinovac of China-To Conduct Clinical Trials in Brazil Photo: AFP / Douglas MAGNO

..

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or [email protected]