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Study Finds Time-Restricted Eating May Help Improve Metabolic Health Outcomes

Study Finds Time-Restricted Eating May Help Improve Metabolic Health Outcomes


Eating a higher daily calorie intake early in the day may help fight weight gain, improve blood sugar volatility, and reduce the time blood sugar stays above normal levels, new research suggests. is suggested in

This type of feeding may prevent progression to type 2 diabetes in pre-diabetic or obese individuals due to its effect on blood sugar levels.. ”

Joanne H. Bruno, MD, PhD, Lead Study Author and Fellow of Endocrinology, NYU Langone Health

The new report, presented at the Endocrine Society Annual Meeting on June 15, evaluated early time-restricted feeding (eTRF), which restricts calories for the first eight hours of the day. Previous studies have found that this form of intermittent fasting may improve cardiometabolic health and blood sugar levels. However, the research team wanted to determine whether these improvements were related to weight loss or fasting strategies.

The study, led by researchers at New York University’s Grossman School of Medicine, is the first to assess the effects of early, time-restricted nutrition on blood sugar and inflammation, independent of weight loss.

For the study, the researchers recruited 10 participants with prediabetes and obesity who had both eTRF (80 percent of calories burned by 1:00 p.m.) and normal eating patterns (calories burned after 4:00 p.m.). 50 percent) were compared.

Patients were randomized to eTRF or normal eating patterns for the first 7 days and switched to the alternative group for the next 7 days. To determine the weight-independent efficacy of this strategy, food was provided to meet the patient’s caloric needs for weight maintenance. Patients wore continuous glucose (blood sugar) monitors throughout the study.

“Just one week of eTRF feeding reduced the time these people had high blood sugar levels,” said study lead author Jose O. Aleman, M.D., Ph.D., assistant professor of endocrinology, diabetes, and internal medicine. Metabolism, New York University Grossman School of Medicine. “Research shows that consuming the majority of calories early in the day reduces the time it takes for blood sugar levels to rise, thereby improving metabolic health.”

Dr. Aleman and colleagues found that the weight of the participants remained stable throughout the study. Early time-restricted feeding reduced the mean amplitude of glycemic excursions and decreased the time over range (blood glucose >140 mg/dL) compared to the normal eating pattern group. Time within range was similar between the eTRF and normal feeding pattern groups.

“Based on this data, eTRF may be a useful dietary strategy for diabetes prevention,” Dr. Bruno concluded. “Further research is needed to understand the true overall benefits of these intervention strategies.”




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