Health
Genetic and cardiovascular health are factors of dementia risk, respectively
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Genetic and cardiovascular health each contribute in an additive way to a person’s risk of dementia. Sudha Seshadri, MD, and Claudia Satizabal, Ph.D. July 20th in the UT Health San Antonio (US researchers) journal of the University of Texas Health Sciences Center, including Neurology..
The study was conducted by 1,211 participants in the Framingham Heart Study and involved collaborators at Boston University.
Participants with a high genetic risk score based on common genetic variants, including having an allele called apolipoprotein E (APOE) ε4, had more dementia than subjects with lower risk scores and no APOE. The ε4 allele, which was 2.6 times more likely to develop.
Good cardiovascular health, as defined by the American Heart Association index, also means that the risk of dementia is 0.45 times lower than that of poor cardiovascular health. Was shown.
“Each discovery reveals a relationship between heart health and brain health,” said Dr. Sechadori, principal researcher at Framingham Heart Research. She is a professor of neurology at the Long School of Medicine at UT Health San Antonio and a founding director of the University’s Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases.
“We want the results of this study to send a message to the public, which is to exercise, reduce stress and eat. Healthy diet“And regardless of your gene, you may reduce your risk of dementia.”
“It’s essential to start today,” said Dr. Satizabal, an associate professor of vital sciences and a researcher at the Biggs Institute. “According to our findings, Cardiovascular health ease Risk of dementia For people at high genetic risk. ”
Gina M. Peloso et al, Cardiovascular health, genetic risk, and dementia risk in the Framingham Heart Study, Neurology (2020). DOI: 10.1212 / WNL.0000000000010306
Quote: Genes, cardiovascular health, dementia risk factors (July 21, 2020), https: //medicalxpress.com/news/2020-07-genes-cardiovascular-health-factor-dementia.html to 2020 Obtained from July 21, 2016
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