Keeping Our Infant and Older Adult Populations RSV-Free This Season

Respiratory syncytial virus (RSV) is a respiratory virus that is quite common, typically manifesting as an upper respiratory tract infection with symptoms including sneezing, cough, nasal congestion, and rhinorrhea. In these cases, symptoms typically resolve in 1 to 2 weeks.^1-3

Image credit: photoopus | stock.adobe.com

However, RSV can be serious, especially for infants and the elderly, progressing to involvement of the lower respiratory tract and presenting as more of a bronchiolitis picture, sometimes requiring hospitalization for these populations.^2,3 If severe enough, RSV can go on to result in hypoxia, apnea, and acute respiratory failure. In the United States, it is estimated that between 60,000-160,000 of those adults 65 years of age and older are hospitalized due to RSV each year, while between 58,000 and 80,000 of those younger than 5 years are hospitalized.² Table 1 includes risk factors for both children and adults.

Table 1: RSV Risk Factors

Annual outbreaks of RSV tend to start in the fall, with the peak occurring during the winter months. The spread of RSV occurs through respiratory droplets. Following infection, individuals will remain contagious for roughly 3 to 8 days. Interestingly, there is no long-term immunity produced following infection, thereby increasing vulnerability for reinfection. It is thought that nearly 90% of children will have been infected within their first 2 years of life and RSV will continue to reinfect older children and adults.^2,3

When it comes to RSV season, prevention is key. There have been several new advances in terms of RSV vaccine and monoclonal antibody development in this year alone, adding to palivizumab (Synagis; Sobi) which is the monoclonal antibody currently on the market for the prevention of severe RSV disease in select pediatric populations.⁴ On May 3, 2023, the FDA approved the first RSV vaccine, Arexvy, for those 60 years of age and older.⁵ Then, on May 31, 2023, the FDA approved the second RSV vaccine, Abrysvo, for those 60 years of age and older.⁶ Additionally, on August 21, 2023, the FDA approved Abrysvo as a maternal RSV vaccine, administered to pregnant women who are 32 to 36 weeks along in pregnancy in order to provide an expected 6 months of protection for their infant.⁶ Lastly, on July 17, 2023, Beyfortus, the second monoclonal antibody targeted against RSV, was approved by the FDA.⁷ Table 2 includes indications, administration schedules, and efficacy data for all 4 of these options.

Indications, Administration Schedules, and Efficacy Data

It will be interesting to see RSV hospitalization rates over this upcoming season following the rollout of RSV vaccines and monoclonal antibody administration.

References

1. Jain H, Schweitzer JW, and Justice NA. Respiratory Syncytial Virus Infection. StatPearls [Internet]. Updated June 20, 2023.

2.Respiratory Syncytial Virus Infection (RSV). Centers for Disease Control and Prevention (CDC). Reviewed August 4, 2023.

3. Vaccines and Preventable Diseases – RSV. Centers for Disease Control and Prevention (CDC). Reviewed September 28, 2023.

4. Synagis (palivizumab) [Package Insert]. MedImmune. March 2014.

5. Arexvy – Respiratory Syncytial Virus Vaccine, Adjuvanted [Package Insert]. GlaxoSmithKline. May 2023.

6. Abrysvo – Respiratory Syncytial Virus Vaccine [Package Insert]. Pfizer Laboratories Div Pfizer Inc. August 2023.

7. Beyfortus (nirsevimab-alip) [Package Insert]. AstraZeneca. July 2023.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos