Health
How type 2 diabetes medications can help reduce symptoms
- A new diabetes drug appears to be effective in treating depression-like symptoms in mice.
- Researchers say that reproducing these results in humans could pave the way to treatments for depression with fewer side effects than current chemical antidepressants.
- They added that this study advances understanding of the link between metabolic factors in the body and psychological states.
It is a type 2 diabetes treatment that belongs to the . drugs in the same class Weight loss drugs Ozempic and Wigovy could be a new treatment for depression, according to a researcher.
The researchers reported that they administered the following treatments to mice: dulaglutide — Long-acting glucagon-like peptide-1 receptor agonist (GLP-1) — reduced depression even after exposure to 4 weeks of chronic stress compared to control mice that received no treatment under the same conditions. Along with the medication, which had less disease-like behavior.
“Currently, widely available drug treatments are synthetic chemical antidepressants, which take weeks or months to elicit a response, have some side effects, and can even be toxic at high doses. ” wrote the study authors. “Therefore, new treatments with fewer side effects and higher efficacy are urgently needed.”
The scientists also observed chemical changes in the mice, including 64 different metabolites affected by the drug and four chemical pathways that appear to induce depression-like behavioral changes.
These findings follow similar mouse studies on dulaglutide, which suggest that dulaglutide may improve vascular dementia, enhance memory performance, and reduce cognitive disorders such as Alzheimer's disease. pointed out the study authors.
“Overall, this is a robust animal model study,” he said. Dr.Jagdish HubchandaniHe is a public health professor at New Mexico State University but was not involved in the study.
“The challenge…is that the impact on human health is unknown, and depression is a complex disease that affects multiple parts of the brain, so it wasn't investigated in this study, so all parts of the brain were studied.” “It has not been done,” he said. Today's medical news.
Dr. Angela FitchThe president of the Obesity Medicine Society and Knownwell's chief medical officer agreed.
“We don't know if this applies to humans, but we do have a good understanding of some of the mechanisms behind GLP-1 and mood and behavior. This whole thing requires further research.” said Fitch, who was not involved in the. Today's medical news.
It may seem surprising that a class of drugs called GLP-1 agonists may be effective in treating neurological conditions such as diabetes, obesity, and even depression, but experts say It states that there are good social and cognitive reasons for the association.
“Several metabolic disorders, such as obesity and diabetes, are major risk factors for depression,” the study authors noted. “Indeed, the successful application of antidiabetic drugs in the treatment of neurological diseases suggests that similar drugs may also have beneficial effects on depression.”
“Activation of the GLP-1 receptor does many wonderful things for the human body and is good for us for many reasons,” Fitch said. “Activation of GLP-1 receptors can cause a variety of changes in neurotransmitters that directly affect our mood. Weight issues can cause problems with sleep and activity (for reasons such as joint pain). The more weight you lose, the better you sleep, the more you move, and the better you feel.”
In turn, GLP-1 RAs may also be able to influence how the body produces and expends energy.
“GLP-1 agonists affect energy metabolism, so changes in energy production and expenditure can have multiple effects on brain function,” Khubchandani said. “Further research is also needed into the long-term effects on brain structure.”
So far, studies using dulaglutide to treat depression and other neurological conditions have been limited to animal studies. That means more research is needed and more time is needed before these treatments are tested and deemed safe and effective for humans.
But experts say these studies are needed to learn about the mechanisms of an increasingly popular class of drugs.
In the meantime, if you're experiencing symptoms of depression, experts advise seeking help from a mental health professional.
“Mood changes should not be taken lightly,” Fitch said. “Healthy nutrition, quality sleep, and more physical activity can also help improve your mood, but sometimes medication is needed to treat depression. Look at your big picture and assess your mood, It's important to have a doctor who can help you optimize your lifestyle, your weight, and how it all relates to each other. A holistic, holistic approach to your overall health of body and mind is important.”
|
Sources 2/ https://www.medicalnewstoday.com/articles/can-a-diabetes-drug-lessen-symptoms-of-depression The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
 |
 |
 |
