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New study confirms genetic component of PTSD | News

New study confirms genetic component of PTSD | News


DNA genome testing, genome map. Big data visualization. Abstract infographic representation.

April 24, 2024 – New Genes study More than 1.2 million people have identified 95 genetic loci, or locations, around the globe. genomeis associated with the risk of developing Post-traumatic stress disorder (PTSD)exposure to trauma can impair a person's quality of life with symptoms such as intrusive thoughts and mood instability.

This discovery further validates the role that genetics plays in the disease and may lead to new prevention and treatment strategies.

Harvard University TH Chan School of Public Health Kalestan Coonen He is the senior author of the study, which comes from the National PTSD Working Group. Psychiatric Genome Consortium and Cohen Veterans Biosciences. The study was published April 18 in the journal Nature Genetics.

Dr. Koenen called the study results a “milestone in PTSD genetics” in a press release. Extensive research labs at MIT and Harvard University. Koenen, a professor of psychiatric epidemiology at Harvard Chan College, is a researcher at the Stanley Center for Psychiatric Research at Broad College.

For this study, Koenen and colleagues examined 88 different genome-wide association studies, or genetic data from large groups of people, to determine associations between specific regions of the genome and the risk of developing specific diseases. We reviewed the data from the studies we investigated. The study found 95 genetic loci strongly associated with PTSD risk and 43 genes that appear to play a role in PTSD causation.

Read the Broad Institute's press release about this study. Scientists discover 95 regions of the genome associated with PTSD

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