Study of five women suggesting estrogen, a contraceptive that provides some protection against COVID-19-Technology News, Firstpost

tech2 news staffAugust 6, 2020 12:38:15 IS

Higher levels of estrogen may provide some protection against new coronavirus infections, according to findings from a study of more than 5,000,000 women led by King’s College in London.

Researchers examine data from the COVID-19 Symptom Tracker app across the UK, COVID-19 in Postmenopausal Women, Premenopausal Women With Oral Contraceptives, and Postmenopausal Women With Hormone Replacement Therapy (HRT) during the 5 Weeks May 7-June 15, 2020 Focus on the fashion.

The female sex hormone, estrogen, is naturally reduced in postmenopausal women. It is known to affect the immune system in many ways, including Number of immune cells created,and How these cells respond to the infection.. Based on their findings, researchers have suggested that estrogen may protect against COVID-19.

Postmenopausal women, especially those in the 45-50 age group, had a higher predictive risk of COVID-19 than women in other age groups. COVID-19 symptoms commonly reported by women in this age group include anorexia (total or partial loss of odor), fever, persistent cough, and the need for oxygen therapy in hospitals. The study reported. However, these findings were not statistically significant to show a compelling correlation.

Postmenopausal women aged 50 to 65 years who used hormone replacement therapy (HRT) had a higher predicted risk of COVID-19 but were not required to be hospitalized, the study said. Nonetheless, the researchers pointed out that these results also required a dose of salt, as there wasn’t enough information available on the type of hormone therapy used, the treatment, and the duration of treatment. Did. , And any comorbidities they may have had.

Graph of changes in sex hormones throughout the menstrual cycle. Image credits: clues

Women in the youngest age group aged 18 to 45 who were taking combined oral contraceptives (COCPs) had a lower predicted risk of COVID-19. These tablets contain low doses of both estrogen and progestogen hormones, much like what the body naturally produces. Young women taking these drugs had significantly lower hospitalization rates with fewer symptoms such as cough, delirium, anorexia, anorexia, fatigue, and pain.

From the first week of the COVID-19 pandemic, researchers have noticed a higher number due to the disproportionate proportion of men and older at risk of severe coronavirus disease, but younger and females are relatively helpful. ..

Combining these new findings with studies of past epidemics such as SARS (SARS-CoV) and MERS, estrogen-related protection against COVID-19 in men and older women of all ages compared to young women. He says he can explain the high risks.

New research provides clues as to what the biological basis of these differences is. Preprint survey published in medRxivNot yet peer reviewed.

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