Health
FDA recommends updating COVID-19 vaccine to target KP.2 strain
of The Food and Drug Administration on Thursday The ministry had recommended that pharmaceutical companies develop coronavirus vaccines targeting the KP.2 strain, a descendant of the highly contagious JN.1 variant that began spreading widely in the United States this winter.
The announcement was made after a unanimous FDA advisory committee voted COVID-19 vaccines scheduled for release in autumn will be updated to target the JN.1 variant or any of its descendants.
After the vote, there was disagreement between committee members and Dr. Peter Marks, the agency's top vaccine regulator, about which strain the agency should choose. Most committee members JN.1 takes precedenceMarks preferred to select new strains, KP.2 etc..
“We're paying an incredibly high premium for the mRNA vaccines to get the freshest vaccine,” Marks said, likening getting the vaccine to buying milk at the store.
After the committee meeting, the FDA initially notified the drug company on June 6 Targeting the JN.1 strainBut the FDA continues to monitor strains in circulation, and “based on the most recent available data and the recent increase in COVID-19 cases in areas of the country, the FDA has further determined that, where possible, the JN.1 lineage will be preferred for the updated vaccine,” the FDA said.
The JN.1 is hardly in circulation in the United States. Centers for Disease Control and PreventionAs of Saturday, KP.2 accounted for 22.5% of new coronavirus cases in the U.S., while its sister variant, KP.3, accounted for 25% of new cases.
The FDA's decision allows pharmaceutical companies to begin manufacturing and distributing the vaccine, which is expected to be used as part of COVID-19 vaccination campaigns this fall.
Three pharmaceutical companies, Pfizer, Moderna, and Novavax, are producing coronavirus vaccines. Pfizer and Moderna's vaccines are mRNA-based, while Novavax's vaccine is protein-based. Because protein-based vaccines take a long time to produce, Novavax has indicated that it will not be able to produce the KP.2 vaccine by the fall. Instead, it plans to distribute the JN.1 vaccine that it has already produced.
This is the third vaccine update to target circulating strains, and the selection process for the next vaccine is becoming routine, similar to the annual influenza vaccination update, with vaccinologists selecting the strains in the spring and vaccination campaigns being conducted in the fall.
At the advisory committee meeting, the pharmaceutical company presented data showing that compared to current vaccines that target the variant XBB.1.5, which is not currently in circulation, the JN.1 vaccine should generate higher levels of antibodies against circulating virus strains.
The committee did not recommend who should get the latest vaccine, leaving that to the CDC, which will be holding its own advisory committee meeting later this month.
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Sources 2/ https://www.nbcnews.com/health/health-news/fda-recommends-covid-vaccine-update-target-kp2-strain-rcna157089 The mention sources can contact us to remove/changing this article |
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