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Rare drug-resistant strain of seasonal flu discovered in US

Rare drug-resistant strain of seasonal flu discovered in US

 


June 13, 2024 – The CDC detects two cases of influenza that are resistant to the most commonly used antiviral flu drug known by the brand name Tamiflu.

Laboratory tests have found that two samples of influenza virus in the United States showed two major mutations that arose from influenza A(H1N1), the most common seasonal flu.

Seasonal influenza viruses are different from the avian influenza viruses that have recently been reported to infect cattle and humans.

The Tamiflu-resistant H1N1 virus has two mutations called I223V and S247N. The U.S. cases were identified by the CDC during its annual analysis of flu samples from the U.S. and abroad.

A total of 101 samples were identified as the “double mutant” version of H1N1, and the samples were taken from a total of 15 countries across five continents. The oldest sample was taken in Canada in May 2023, and the most recent sample was taken in Europe in January-February 2024. The Netherlands had the most samples of the double mutant influenza virus, with 30.

The mutated virus was not resistant to other less commonly used antiviral drugs, he said. report CDC Journal Emerging infectious diseasesDouble mutants of influenza viruses First reported The scientists published the findings in the journal Nature earlier this year. Lancet MicroorganismThey were studying influenza samples collected in Hong Kong in October 2023.

Influenza antiviral medications reduce the severity of influenza and the duration of symptoms. Some studies have shown that taking these medications reduces the risk of death in adults hospitalized with influenza. These medications work best if started within 1-2 days of the onset of symptoms.

Since October 2023, an estimated 35 million people in the U.S. have been sickened by the flu, with 390,000 hospitalizations and 24,000 deaths, according to the CDC's weekly report. Influenza View Publications. Of influenza specimens tested in U.S. public health laboratories, 76% were influenza A and the remainder were influenza B.

Among hospitalized adults, COVID-19 has a slightly higher mortality rate than influenza, according to the study. analysis Recently Published Journal of the American Medical AssociationThe 30-day mortality rate for adults hospitalized with COVID-19 in 2023-2024 was 5.7%, compared with 4.7% for adults hospitalized with influenza during the same period. The authors noted that COVID-19 caused twice as many hospitalizations as influenza.

Sources

1/ https://Google.com/

2/ https://www.webmd.com/cold-and-flu/news/20240613/rare-form-of-drug-resistant-seasonal-flu-detected

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