Do you feel dizzy when you stand up? Warn researchers of high risk of dementia

Researchers say people who get up and feel dizzy or light-headed may be at increased risk of developing dementia after a few years. A condition called orthostatic hypotension occurs when your blood pressure (BP) suddenly drops when you stand up.

The authors found that only people with reduced systolic blood pressure (the pressure in the blood vessels when the heart beats) are associated with dementia. Resting) or their blood pressure throughout. Systolic blood pressure is the first or highest number of blood pressure readings.

For analysis, systolic orthostatic hypotension was defined as a drop in mercury (mmHg) of at least 15 millimeters after standing from a sitting position. “We need to monitor blood pressures from the time a person sits down to standing. Controlling these blood pressure drops could be a promising way to maintain thinking and memory in the elderly. there is” explain Dr. Laure Rouch of the University of California, San Francisco, in an analysis published in the research author Neurology, it is the official journal of the American Academy of Neurology.

Dementia is one of the leading causes of disability and dependence in older people worldwide. It is a syndrome with a diminished ability to perform memory, thoughts, actions, and daily activities. World wide 50 million According to the World Health Organization (WHO), people with dementia have nearly 10 million new cases each year.

The research team, funded by the National Institute for Aging, was attended by 2,131 people with an average age of 73 years and no dementia at the time of enrollment.
“Orthostatic hypotension is associated with an increased risk of cardiovascular events and all-cause mortality, but its association with cognitive outcomes is less clear. Therefore, the purpose of our study was to assess repeated blood pressure. Was to investigate the association between postural changes in postural change. Orthostatic hypotension, visit-to-visit variability of postural changes in blood pressure, risk of dementia in a prospective study of health, aging, and body composition (Health ABC).” The team says.

Blood pressure measurements of study participants were obtained at the beginning of the study and at 1, 3, and 5 years. A total of 15% had orthostatic hypotension, 9% systolic orthostatic hypotension, and 6% diastolic orthostatic hypotension. Over the next 12 years, participants were evaluated to see if anyone had dementia. Analysis reveals that a total of 462 or 22% have developed the disease.

Researchers found that people with systolic orthostatic hypotension were about 40% more likely to develop dementia than people without the condition. An estimated 26% or 50 of 192 people with systolic orthostatic hypotension developed dementia, whereas 21% or 412 of 1,939 people without dementia developed dementia. When the authors adjusted for other factors that could affect dementia risk, such as diabetes, smoking, and drinking, people with systolic orthostatic hypotension were 37% more likely to develop dementia ..

Researchers also show that those who have the most variable systolic blood pressure measurements between sitting and standing with each visit develop dementia one year later than those with stable readings. I also discovered that it is very likely. People were divided into three groups based on how much their measurements changed over time. A total of 24% of people in the group with the most variability in systolic readings later developed dementia, while 19% of people in the least variability group had dementia. When the team adjusted for other factors that affected dementia risk, people in the highest group were more likely to develop dementia by 35% than those in the lowest group.

Researchers note that studies are observations and have no cause or effect. Only the association between blood pressure readings and the onset of dementia is shown. “In this study, systolic orthostatic hypotension, rather than systolic orthostatic hypotension assessed at several time points, was associated with increased risk of incident dementia at 12 years of follow-up. This relationship was independent of demographics and medical complications. Variations in postural changes in systolic blood pressure were associated with an increased risk of dementia. It raises the issue of potential preventive interventions to control variability,” the authors said.

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