Health
New tests may predict which newborns are most at risk for type 1 diabetes
Toronto-The new test does the best job of predicting which babies are at the highest risk of developing type 1 diabetes, the researchers say.
Type 1 diabetes occurs when the pancreas does not produce enough insulin to regulate the body’s blood sugar. Unlike type 2 diabetes, which is associated with obesity and other lifestyle habits, type 1 diabetes cannot be prevented.
It also mainly affects young people. An estimated 90% of people with type 1 diabetes worldwide are younger than 25 years. About 40% of children with type 1 diabetes develop a complication called ketoacidosis, which can be fatal, especially in the youngest children.
Ketoacidosis is usually treated only after diabetes is discovered. There are preventative treatments, but they are rarely used because it is difficult to determine which child is at highest risk until type 1 diabetes develops.
Now, researchers at the University of Exeter in the UK and the Pacific Northwest Institute in the US say they have found a more accurate new way to predict which babies will develop type 1 diabetes-preventive treatment May open up the possibility of.
“Using our new composite approach, identifying which babies develop diabetes can prevent these tragedies and ensure that the child is on the right course of treatment early in life. Lauric Ferrat, the lead author of the study and the applied mathematician of Exeter, Said in a statement..
As outlined on Friday Letter issued by Journal Nature MedicineResearchers have developed a “complex risk score” test that takes into account genetics, a family history of diabetes, biomarkers known to be associated with type 1 diabetes, and other factors, the researchers say. Says.
Taking all of these factors together, the researchers said, “Predicting whether a child under the age of 2 will have type 1 diabetes before the age of 1 will develop which child will develop type 1 diabetes. It was possible to improve that prediction dramatically”8.
In addition, their tests say that they enable much more efficient screening of newborns to prevent ketoacidosis.
The test is currently being tried in Washington. The researchers say the same approach could potentially be used to predict whether the newborn will develop other pediatric diseases that are strongly associated with genetics, including celiac disease.
Type 1 diabetes is less common than type 2 diabetes, affecting approximately 10% of all diabetic patients worldwide.
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