Health
Caffeine and coffee are associated with reduced risk of cardiometabolic diseases
HealthDay News — Habitual coffee and caffeine consumption is associated with a lower risk of new-onset cardiometabolic morbidity (CM), according to a study published online in HealthDay News. Journal of Clinical Endocrinology and Metabolism.
Xujia Lu from Suzhou Medical College, Soochow University, China, and colleagues investigated the association of coffee, tea, and caffeine intake with CM, defined as the comorbidity of at least two of the following conditions: type 2 diabetes, coronary artery disease, or stroke. The study included 172,315 (caffeine analysis) and 188,091 (coffee and tea analysis) participants who were free of cardiometabolic disease at baseline. 168 metabolites were measured in 88,204 and 96,393 participants, respectively.
The researchers observed a nonlinear inverse correlation. coffeeAssociations were found between coffee, tea, and caffeine intake and the risk of new-onset CM. Moderate coffee (3 cups/day) or caffeine (200-300 mg/day) consumers had the lowest risk of new-onset CM compared with non-consumers or those consuming less than 100 mg of caffeine/day, with hazard ratios of 0.519 and 0.593, respectively. Moderate coffee or caffeine intake was inversely associated with the risk of almost all stages of CM development, including progression from disease-free to a single cardiometabolic disease to CM. The associations between coffee, tea, and caffeine and CM were significantly higher than those between coffee, tea, and caffeine and CM. Caffeine intake Between 80 and 97 metabolites, including lipid components within very low density lipoproteins, histidine, and glycoprotein acetyl, were identified in the occurrence of CM.
“The findings highlight that encouraging moderate coffee and caffeine consumption as a dietary habit in healthy people may have far-reaching benefits in preventing CM,” the authors wrote.
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