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Should I get the RSV vaccine? > News > Yale Medicine
[Originally published: July 24, 2023. Updated: Oct. 7, 2024]
This winter, when the usual sneezing, wheezing, coughing and fever set in, you can get extra protection for people who are at higher risk for at least one common illness. respiratory syncytial virus (RSV) It causes mild cold symptoms in most people, but it can cause hospitalization and death in the elderly and infants. However, vaccinations are now being given to the elderly, infants, and pregnant women who want to protect their newborns.
“There are a lot of changes happening with RSV,” he says Dr. Scott Robertsan infectious disease specialist at Yale Medicine. “Attempts to create a vaccine have been made for decades, but have failed for a variety of reasons.”
One turning point came with the study of an RSV protein called RSV fusion (F), which provides a powerful stimulus to the immune system. This study paved the way for clinical trials showing positive results.
Vaccines for the elderly are important. One reason for this, Dr. Roberts explains, is that older people's immune systems weaken with age and are unable to fight off infections such as respiratory syncytial virus (RSV) as well as they could when they were younger. Children have smaller lungs, which makes them more susceptible to serious illnesses.
There are currently three RSV vaccines available for people age 60 and older to choose from. They are ABRYSVO® from Pfizer. AREXVY® by GSK. and mRESVIA®, manufactured by Moderna.
The Centers for Disease Control and Prevention (CDC) recommends that all adults age 75 and older and those ages 60 to 74 with risk factors for severe RSV disease, such as chronic heart or lung disease, a weakened immune system, or other medical conditions. We recommend that adults: If you have diabetes or live in a nursing home, get one of the three RSV vaccines. (However, the CDC says if you got the RSV vaccine last year, you don't need to get the RSV vaccine this year.)
In addition, there are two options for infants and young children: all infants up to 8 months of age born or entering the first RSV season, and nilcevimab (commercially available) for small groups during the RSV season. This includes a monoclonal antibody called Beyfortus®. The second season is for children aged 8 to 19 months who are at high risk for severe disease (including those with severe immunodeficiency).
ABRYSVO is also approved to protect newborns from birth to six months of age from severe RSV when given to pregnant women ahead of RSV season to provide antibodies that can be passed on to the fetus.
with Dr. Roberts Thomas Murray, MDDr. Pediatric Infectious Disease Specialist at Yale Medicine answered questions about new options for seniors and children.
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