This is why the coronavirus attacks these organs rather than other organs, research

With outbreaks of coronavirus or COVID-19 worldwide, scientists are addressing the various properties of the new virus and how it affects the human body. But since the beginning of the pandemic, researchers have struggled to understand why the virus affects only the heart, kidneys, and liver, and not other organs.

A new study in Spain now claims that proteins found in the lung act as primary activators. A team of researchers at the University of Zaragoza and Fundacion Agencia Aragonesa para la Investigacion y el Desarrollo have discovered that lung proteins are caused by viruses. This activates proteins in certain organs, making them more susceptible to infection.

Coronavirus does not affect all organs

The new virus uses a protein on the outside of the cell called angiotensin converting enzyme 2 (ACE2) to invade and infect cells. After entering viral cells, viral proteins can come into contact with proteins in the body and cause mild or severe effects.

However, not all organs rich in ACE2 are affected by the virus. This must be the scientist’s claim that the transmission route is different. “This receptor is ubiquitous in most human organs, and if the virus circulates in the body, it can also invade and affect other organs.” Department of Applied Mathematics, University of Zaragoza Said.

“But the virus does affect some organs, but not some, as one might expect from these potential mechanisms,” he added. Daily email.. In a study published in the journal Chaos, the team examined how proteins prevalent in the lungs communicate with proteins in other organs.

Estrada said that proteins must move in a “non-diffusing” manner within cells in order for them to interact. He described a movement similar to a drunk walking on a crowded street. Intracellular proteins must bypass obstacles to interact, but very few are present in the same cell or organ, and others are not.

Estrada has created a mathematical model showing that 59 proteins, the major activators of other organs, are found in the lungs. When a new virus affects the lungs, it drives a series of events that cause changes in proteins in other organs.

However, these changes occur in certain organs such as the heart and kidneys, not in the stomach. “By targeting some of these proteins in the lung with existing drugs, we prevent disruption of proteins expressed in organs other than the lung, avoid multiple organ failure, and often lead to patient death.” He said.

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