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Malaria discovery may facilitate antiviral treatment of COVID

 


Dr. Julian Drousse of Royal Melbourne Hospital at the Victoria Infectious Diseases Reference Lab (VIDRL) ​​at the Doherty Institute, a co-founder of the grant, was part of a team that initially propagated and shared the virus responsible for COVID-19. did. He said the study was an important contribution to the effort to defeat the pandemic.

Professor Peter Reville, senior medical scientist and leader of hepatitis B research at Doherty Institute at Royal Melbourne Hospital, said the approach developed by the RMIT team is truly exciting.

“It has been proven successful with other human pathogens, including malaria and hepatitis C virus, and is very much used to discover novel drug targets for hepatitis B and COVID-19. There is a realistic outlook,” he said.

This paper is an RMIT-led international collaboration with researchers at Monash University in Melbourne, Dr. Danny Wilson (Director of the Institute of Malaria Biology at the University of Adelaide, Barnett Institute), and Dr. Jean-Philip Saint Bratte (French Government Agency, Inselme, Paris). It is the result of cooperation. Professor Oliver Billker (Umeå University, Sweden, Wellcome Sanger Institute, UK).

The paper “Analysis of erythrocyte signaling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial interventions” is published in Nature Communications (DOI: 10.1038 / s41467-020-17829-7). ..

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