Health
Cordyceps sinensis 'could lead to new cancer treatments'
A type of fungus that grows in caterpillars may slow the growth of cancer cells, a new study has found.
Cordycepin, a chemical produced by parasitic fungi that infect animals, interacts with genes and blocks cell growth signals.
Scientists at the University of Nottingham's School of Pharmacy said the discovery could lead to the development of new drugs to treat the disease.
Cordyceps sinensis It has been used as a medicine and is also a delicacy. For many years in parts of Asia.
According to the study, published in the journal FEBS Letters, cordycepin is produced by Cordyceps sinensis, an orange fungus that infects Cordyceps sinensis.
Scientists measured the effects of chemicals on genes and compared their effects to other treatments.
They discovered that cordycepin blocks cell proliferation signals that are overactive in cancer.
“Our data support cordycepin as a good starting point for new cancer drugs and explain its beneficial effects,” said Cornelia de Moor, from the university's School of Pharmacy.
“For example, derivatives of cordycepin could aim to create the triphosphate salt of the drug, which has the same effect.
“Furthermore, our data points to specific genes whose activity reliably responds to cordycepin, so this data could be useful for monitoring the effects of cordycepin in patients, which could be measured, for example, in blood cells. .”
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