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Researchers identify biomarkers indicating risk of COVID-19 complications

 


(WXYZ) — Could a blood test predict if COVID-19 is fatal?

Researchers at George Washington University have identified five major biomarkers that are believed to indicate how fatal a person infected with COVID-19 can become.

These five biomarkers are basically medical indicators found in the blood. It may also indicate a risk of complications such as inflammation and bleeding disorders. Researchers understood this by examining the blood of 299 patients with COVID-19. And what they found was that all 200 of these people carry these five biomarkers. And higher levels were associated with several things: increased risk of admission to the intensive care unit, increased risk of requiring invasive ventilator support, and, sadly, of death. increase.

The five biomarkers are:

• Interleukin 6 or “IL-6” for short. These are the cytokine immune cells that can indicate if inflammation has gone out of control.

• Then there is what is called “D-dimer”. These are degraded proteins that can signal when blood vessels are under attack.

• The third biomarker is C-reactive protein or CRP for short. The liver releases these in response to inflammation.

• The fourth marker is lactate dehydrogenase or LDH. The body sends this enzyme to heal damaged tissues.

• And finally, a protein called ferritin. Helps cells store iron. Also, too much or too little ferritin can lead to anemia and infections that interfere with the functioning of blood cells.

There are two biomarkers (LDH and D-dimer levels) that indicate an increased risk of death. The higher the number, the higher the risk of death, based on research. But on the plus side, these five biomarkers really help doctors understand which patients may need early treatment or ventilator support.

Doctors are currently using common risk factors. For example, we are using patient age, obesity, and potential health conditions such as heart disease to find out who may develop a serious illness. We hope, therefore, that a simple blood test examining these biomarkers will help treat patients and survive a severe COVID-19 infection.

Additional information and resources about Coronavirus:

Click here for pages with resources Overview of COVID-19 from the CDC, details of Michigan cases, timeline of Governor Gretchen Wittmer’s order since its outbreak, coronavirus’s impact on Southeast Michigan, links to more information from the Michigan Department of Health and Human Services , CDC and WHO.

Show Global Coronavirus Tracker With data from Johns Hopkins University.

See our full coverage Coronavirus continuous news page.

Visit us Rebound detroit, Where we are working to help people financially affected by the coronavirus. We have all the information available to help you through this crisis and all the information on how to access it.

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