Health
Are you taking paracetamol too often? We advise you to be careful! New study warns 'safe' drugs may have serious side effects
A recent study found that paracetamol, a widely used over-the-counter drug and generally recognized as 'harmless', may increase the risk of gastrointestinal, heart and kidney complications in adults over 65. It turns out that there is.
Paracetamol is commonly taken to relieve mild to moderate fevers and is also a first-line treatment for osteoarthritis, a chronic disease that causes joint pain, stiffness and swelling due to wear and tear. It is often preferred for its effectiveness, safety, and ease of access.
However, some studies question its effectiveness in pain relief, while others suggest that long-term use may increase the risk of gastrointestinal side effects such as ulcers and bleeding.
A new study conducted by the University of Nottingham in the UK found that paracetamol use increased the risk of peptic ulcer bleeding (bleeding from an ulcer in the gastrointestinal tract) by 24% and lower gastrointestinal bleeding by 36%. It turned out. Additionally, the risk of chronic kidney disease increased by 19 percent, the risk of heart failure increased by 9 percent, and the risk of hypertension increased by 7 percent.
“This study highlights the significant gastrointestinal, cardiovascular and renal side effects in older people who are repeatedly prescribed paracetamol in the UK,” the authors wrote, published in the journal Arthritis Care and Research. stated in the study.
Lead researcher Weiya Zhang, from the University of Nottingham's medical school, said: “Due to its perceived safety, paracetamol has long been the preferred first-line treatment for osteoarthritis, especially in older people who are more susceptible to drug-related complications. “It's been getting worse,” he explained.
Professor Zhang also highlighted the need for further research, saying, “Given its limited analgesic efficacy, paracetamol as a first-line analgesic for long-term conditions such as osteoarthritis in the elderly” Its use should be carefully reconsidered.”
For their analysis, researchers looked at the health records of 1,80,483 people aged 65 and above who had been repeatedly prescribed paracetamol (prescribed more than once within six months). Their health outcomes were compared with those of 402,478 people of the same age who had not been prescribed the drug repeatedly.
This study analyzed data from Clinical Practice Research Datalink-Gold, focusing on participants who registered with UK general practitioners between 1998 and 2018.
In a related 2016 study published in The Lancet, researchers at the University of Bern analyzed data from 76 randomized trials involving 58,451 patients conducted between 1980 and 2015. did. They found that paracetamol did not provide significant pain relief or improvement in physical function in knee patients. and osteoarthritis of the hip.
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Sources 2/ https://www.businesstoday.in/science/story/popping-a-paracetamol-too-often-caution-advised-new-study-warns-safe-drug-can-have-serious-side-effects-457364-2024-12-15 The mention sources can contact us to remove/changing this article |
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