Health
Cigarettes or vapes, choose your poison.
Electronic cigarette use, or vaping, is growing in popularity, and with it the availability of MODs and VAPE flavors to suit every style and palette. But is this popular habit actually harmful? “E-cigarettes have been used as a smoking cessation approach to avoid exposure to carcinogens.” Dr. Lawrence Fungnewly appointed Scientific Director of the Center for Integrative Immunotherapy Research and Professor in the Department of Translational Sciences and Therapeutics at the Fred Hutchinson Cancer Center. But “our study shows that e-cigarettes may not be as harmless as previously believed.” Dr. Fung, who recently joined Fred Hutch from UCSF, is conducting the research described here. was held. The Fong lab uses cancer cell lines and preclinical mouse models of several cancer types (melanoma, colorectal cancer, prostate cancer) to study the effects of e-liquids on cancer. I did. E-liquid contains inert ingredients: propylene glycol (PG), an odorless and tasteless liquid used in antifreeze, and vegetable glycerin (VG), which when heated helps aerosolize nicotine or cannabis for inhalation. It is. Researchers found that these inactive ingredients, alone or in combination with nicotine, can increase cancer metastasis to the lungs and suppress the immune system, which is important for cancer immunotherapy-based treatments. I discovered. Their discovery is Frontiers of immunology.
It may seem logical that inhaling foreign objects into your lungs can be harmful, but e-cigarettes are safe for those looking to find an alternative to cigarettes, cigars, and pipes. It may seem like a good alternative. E-liquids containing PG/VG inactive ingredients and nicotine or cannabis are not carcinogenic per se, but rigorous testing of PG/VG alone or in combination with nicotine in cancer models is limited. For this reason, the Fong lab wanted to know how the E-liquid's ingredients, PG/VG and nicotine, affect metastasis and the tumor microenvironment.
Metastasis, or the spread of cancer from its original site to other parts of the body, is an important factor in cancer mortality. To understand how PG/VG alone or in combination with nicotine affects cancer cell migration, researchers conducted studies using cancer cells and preclinical mouse models of cancer. I did. One of the assays used is called a scratch test. This assay measures the movement of cells back to a clean area after wounding a monolayer of cells. The researchers found that when cells were treated with PG/VG, colorectal cancer cells migrated back to the area from which they had been removed much faster than untreated cells. In mouse models of melanoma, colorectal cancer, and prostate cancer metastasis, PG/VG is a common site of cancer metastasis in animals that receive tail vein injections of cancer cells pretreated alone or in combination with nicotine. An increase in cancer metastasis to the lungs was recorded. Inject cancer cells without preconditioning treatment. Furthermore, cancer cells implanted into mice or preconditioned by whole mouse exposure in e-cigarette chambers showed more advanced colorectal cancer metastases in the lungs compared to their respective cancer-bearing controls. (increased the number of tumor nodules and decreased survival in mouse models). Cells or mice were not exposed to PG/VG.
|
Sources 2/ https://www.fredhutch.org/en/news/spotlight/2024/12/tst-arias-badia-frontimmun.html The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
 |
 |
 |
