Health
GLP-1 weight loss drugs may reduce risk of dementia and other diseases
The use of GLP-1 weight loss drugs such as semaglutide (Wegovy) and tirzepatide (Mounjaro) is associated with a lower risk of a wide range of diseases, including Alzheimer's disease and dementia, a large study concludes.
US researchers analyzed the use of GLP-1 receptor agonists in the health records of 2.4 million diabetic patients, Reducing the risk of some substance use disorders; coagulation disorders; respiratory diseases including COPD; and inflammatory bowel disease.
Overall, people taking these drugs for diabetes were found to have a lower risk of 42 health conditions associated with use of that group of drugs than people taking other drugs. did.
Reporting natural medicinethey created an atlas of reduced risk conditions. Deep vein thrombosis and heart attack. However, it also includes conditions that appear to be at increased risk in people taking GLP-1 receptor agonists.
Researchers found an increased risk of 19 health problems, including nausea and vomiting, abdominal pain, low blood pressure, fainting and symptoms of gastrointestinal disease such as arthritis, as well as pancreatitis and kidney disease.
The analysis was based on data from the U.S. Department of Veterans Affairs, but the researchers emphasized that it was an observational study and did not prove cause and effect.
Study leader Dr. Ziyad Al Ali, director of the Center for Clinical Epidemiology at Washington University School of Medicine in St. Louis, said of the GLP-1RA drugs: Acts on receptors expressed in brain regions They are involved in impulse control, reward, and addiction, and “may explain their effectiveness in suppressing appetite and addictive disorders.”
“These drugs also reduce inflammation in the brain, resulting in weight loss. Both of these factors improve brain health and may explain reduced risk of diseases such as Alzheimer's and dementia. .”
However, he added that the scale of the associated benefits would be modest.
“However, even if they are less effective, this does not negate the potential value of these drugs, especially in conditions for which few effective treatment options exist, such as dementia.
“This may also mean that these drugs are most effective when used in conjunction with other interventions, such as lifestyle changes or other medications.”
Professor Naveed Sattar, professor of cardiometabolic medicine at the University of Glasgow, said some of the suggested benefits identified in the study, such as a lower risk of heart attack and stroke, were confirmed in randomized controlled trials.
But most others will require future evaluation to confirm or refute.
“The same goes for the suggested risks, some of which are clearly meaningful (e.g. increased nausea and vomiting), but many others are not. However, the findings may simply reflect unmeasured confounding.”
He added: “Fortunately, large randomized trials are underway with GLP-1RA-based therapies that result in greater weight loss, and several trials are expected to be completed within the next 1 to 4 years. It will be reported,” he added. Trials like this will bring us closer to the truth. ”
|
Sources 2/ https://www.pulsetoday.co.uk/news/clinical-areas/gastroenterology-obesity/glp-1-weight-loss-drugs-may-cut-risk-of-dementia-and-other-conditions/ The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
 |
 |
 |
