Connect with us

Health

Pregnant mother’s immune status is associated with behavioral and emotional problems in children with autism

 


Autistic children born to pregnant immune mothers are more likely to have behavioral and emotional problems, a study by UC Davis Health found. This study examined maternal immunity history as a predictor of symptoms in children with autism.

We tested the ability of the maternal immune history to predict the possible role of ASD symptoms and offspring sex. “

Paul Ashwood, Professor and Professor of Microbiology and Immunology at UC Davis MIND Institute

Published on August 14 Translation PsychiatryThe study found that the sex of the child can also interact with the immune status of the mother, affecting results, especially in terms of the child’s cognition.

Maternal immune status and autism

Maternal immune status is caused by dysfunction of the mother’s immune system. They include allergies, asthma, autoimmune diseases, autoinflammatory syndromes and immunodeficiency syndromes. Previous studies have shown that maternal immune status is more common in mothers of children with autism spectrum disorders (ASD).

The researchers enrolled 363 mothers and their children (252 men, 111 women) in the Autism Phenomenon Project (APP) and Neurodevelopment Autism Imaging (GAIN) study at the UC Davis MIND Institute. did. The median age of children was 3 years.

Researchers measured the severity of autism in children and evaluated a range of behavioral and emotional problems such as aggression and anxiety. They also measured child development and cognitive function.

The study found that about 27% of pregnant mothers were immune. 64% of these mothers report a history of asthma, the most common immune state. Other frequent conditions include Hashimoto’s thyroiditis (hypothyroidism), Raynaud’s disease (blood circulation disease), alopecia (hair loss), psoriasis (skin disease), rheumatoid arthritis (joint tissue inflammation). ..

The study also found that maternal immune status was associated with increased behavioral and emotional problems, but not cognitive decline in autistic children.

Does Offspring Gender Interact with the Impact of Maternal Immune Status on Autism Symptoms?

According to the Center for Disease Control and Prevention (CDC), ASD is four times more common among boys than among girls.

“Our study investigated whether sex of offspring could interact with the presence of maternal immune status to influence behavioral outcomes in autistic children,” Ashwood said. .. “Mother’s immune status may be one of the environmental factors contributing to the increased prevalence of men with ASD.”

The study found that a history of maternal immune status was more common in boys with ASD (31%) compared to women (18%). Specifically, asthma was twice as common in mothers of boys with ASD than in girls with ASD.

Studies have also shown that in the case of ASD, where a maternal immune status exists, female offspring are less susceptible to adverse cognitive outcomes in response to maternal inflammation than male offspring.

“This important finding links the sex of the offspring and the immune status of the mother to autism,” Ashwood said. “It provides more evidence that male offspring are at increased risk of adverse consequences due to maternal immune activation as compared to female offspring.”

Future studies will include identifying the type of immune status, severity, timing of pregnancy, and then examining the progeny results over time.

Source:

See journal:

Patel S. other (2020) Maternal immune status is increased in men with autism spectrum disorders and is not associated with behavioral and emotional but cognitive comorbidities. Translational psychiatry. doi.org/10.1038/s41398-020-00976-2..

..

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or [email protected]