Health
Cannabis hospitalization associated with increased risk of dementia
Top Line:
Cannabis-related emergency department (ED) visits or hospitalizations have increased by more than 26 times over 13 years among individuals aged 65 and over, saying they are at a significantly higher risk of dementia than all-caused acute care visits.
Methodology:
- This population-based, retrospective, concordant cohort study included data from 2008 to 2021 for over 6 million people aged 45-105 in Ontario, Canada. Follow-up continued until 2022.
- The researchers identified more than 16,000 individuals in incident encounters (average age, 55 years; 60% of men) with incisive care for cannabis use, including ED visits (76%) and hospitalizations (24%).
- They compared the diagnosis of dementia between patients receiving acute treatment for cannabis use and three other groups. Matched patients receiving all-causal care, a matched general population, and patients receiving acute care for alcohol use.
remove:
- During the study period, the annual acute treatment rate for cannabis use increased by more than five times for ages 45-64 (10.16 to 50.65 per 100,000), and by more than 26 times for ages 65 (0.65 to 16.99 per 100,000).
- The risk of dementia within 5 years was 1.5 times higher in the cannabis-related care group than in the cannabis-related care group and 3.9 times higher than in the matched general population (absolute rate, 5%, 3.6%, and 1.3%, respectively).
- After adjusting for a variety of factors, including other health conditions, the risk of a five-year dementia diagnosis remained higher in patients receiving acute care for cannabis use than in patients receiving all-causal care (adjusted hazard ratios). [aHR]1.23; 95% CI, 1.09-1.39) and the concordant general population (AHR, 1.72; 95% CI, 1.38-2.15).
- However, patients receiving cannabis-related acute care had a lower risk of diagnosis of dementia than patients receiving alcohol-related acute care (AHR, 0.69; 95% CI, 0.62-0.76).
actually:
“Regular cannabis use may directly increase the risk of dementia through changes in brain structure. Regular cannabis use may also increase the risk of hypertension, head injuries, other established risks of dementia, including high risk of depression and social isolation.” press release.
sauce:
The study was led by Daniel T. Milan, MD, University of Ottawa, Ottawa, Ontario, Canada. it was It's published online On April 14th Jama Neurology.
limit:
This study did not examine patterns of cannabis use that do not require acute medical procedures. Detailed data on the duration, frequency and type of cannabis use were not available. Furthermore, residual confounding and inverse causality were possible.
Disclosure:
This study was supported by the Canadian Institute for Clinical Evaluation Science and the Canadian Health Research Project Grant. The authors reported no related conflicts of interest.
This article was created using several editing tools, including AI, as part of the process. Human Editors reviewed this content prior to its release.
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Sources 2/ https://www.medscape.com/viewarticle/cannabis-hospitalization-linked-increased-dementia-risk-2025a10009zt The mention sources can contact us to remove/changing this article |
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