Health
Genetic testing helps predict ovarian cancer survival, says USC researchers – NBC Los Angeles
A study published Monday said USC researchers could more accurately identify survival predictions for women with advanced ovarian cancer, adjust treatments, and predict which patients could benefit from clinical trials. May help identify what is there.
A new study by USC scientists and their international colleagues helps how oncogene testing identifies patients most likely to survive, according to a study published in the Annals of Oncology I’m analyzing
“We envisioned a test to use at diagnosis-it may identify patients who are unlikely to benefit from current treatment and offer them alternatives,” USC and lead author of the study, “for example. These patients may be good candidates for clinical trials and various treatments that may improve survival.”
In addition to Millstein, a member of the USC Norris Cancer Center, another USC author for this study was Anna Wu, Professor of Preventive Medicine at the Keck School of Medicine.
An estimated 21,750 American women were diagnosed with ovarian cancer this year, and researchers have found that the average survival time for the most common and aggressive forms of women is about 4 years. Survival rates vary widely from patient to patient, highlighting the need to estimate who is facing a fast-moving or slow-moving disease.
USC researchers say that oncogene testing, based on tissue removed during surgery for cancer, is more predictive of survival in women with ovarian cancer than usual methods based on patient age and cancer stage. I found that.
For the study, scientists look at stored tumor samples and survival data from about 4,000 women around the world whose information has already been gathered for previous studies and create customized genetic tests. do it
Predict patient 5-year survival.
“Some of the genes identified as predictors of good or bad survival may be potential targets for new treatments,” New South Wales, Sydney, Australia.
“To date, the vast majority of ovarian cancer patients are treated the same. Unlike breast and other cancers, we look at the tumor and choose from a variety of treatments,” she added. Patients may be stratified and more personalized treatments may be offered in the future. “
This research paper included 125 authors across 86 organizations, partly funded by the National Institutes of Health, the U.S. Department of Defense Ovarian Cancer Research Program, and grants from the National Cancer Institute. ..
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