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Antibiotics increase the risk of inflammatory diseases. Scientists find and treat new proteins in the nervous system

 


Antibiotics are magical drugs that help fight microorganisms that enter the body with the intention of doing harm. However, the abuse and misuse of these antibiotics has led to a widespread increase in cases of antibiotic resistance. Not only that, research has shown that the use of antibiotics instead of treating symptoms can cause some inflammatory diseases, including inflammatory bowel disease. So the question is, does antibiotics cause more harm than good?

Antibiotics may increase the risk of developing inflammatory bowel disease

In a recent study published in the journal, Lancet Gastroenterology & HepatologyScientists have discovered that broad spectrum antibiotic use may increase the risk of emerging inflammatory bowel disease (IBD) and other inflammatory diseases such as ulcerative colitis and Crohn’s disease. Did. Broad-spectrum antibiotics are the most commonly prescribed, able to fight bacteria that cause a variety of illnesses.

The study diagnosed 23,982 new patients between January 1, 2007 and December 31, 2016. Ulcerative colitis has 15,951 patients, Crohn’s disease has 7,898, and unclassified IBD has 133. These patients were compared to 28,000 siblings and 117,000 controls from the general population. The results showed that previous use of antibiotics almost doubled the risk of developing IBD.

The results further showed that people who took broad spectrum antibiotics had an increased risk of developing ulcerative colitis and Crohn’s disease.

In this study, scientists concluded that physicians should look for risk factors associated with IBD before they can prescribe antibiotics to patients unnecessarily.

Neuromedin B: a new protein for treating inflammatory diseases

When a foreign microorganism enters the human body, the immune system is activated and develops cytokines (inflammatory cells) to fight the microorganism. This causes a slight inflammation in the locus. However, when the immune system becomes overactive, large amounts of cytokines are released, causing hyperinflammation. This inflammation can cause a variety of inflammatory disorders, including asthma, allergies, chronic fibrosis, and chronic obstructive pulmonary disease (COPD).

Now scientists at Rutgers NJ Medical School have discovered a neuropeptide called Neuromedin B. It is a small protein-like molecule that nerve cells use to interact with each other.

Research published in journal Natural immunologyScientists have discovered that Neuromedin B is known to protect the body from the excess immune system and prevent severe inflammation.

Based on these discoveries, the next step, scientists say, is to use this protein to form useful drugs for the treatment of various inflammatory diseases.

See the following articles for more information: What is an antibiotic..

The Firstpost Health article was created by myUpchar.com, India’s first and largest resource for validated healthcare information. At myUpchar, researchers and journalists work with doctors to provide all health information.

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