A healthy diet is associated with a reduced risk of symptoms that precede Parkinson’s disease

A healthy diet was associated with a reduced risk of concurrent prodromal symptoms of Parkinson’s disease, according to a study published in Neurology, Medical Journal of the American Academy of Neurology.

“Symptoms such as constipation commonly occur in groups, but it is relatively rare for individuals to develop multiple functions that they independently investigated.” Samantha Molesberry,PhD, A postdoctoral fellow at the School of Nutrition at Harvard TH Chan School of Public Health told Healio Primary Care. “Instead, the co-occurrence of multiple features may suggest that there is an underlying disease process that causes them all, including the early stages of Parkinson’s disease.”

To assess how diet is associated with prodromal Parkinson’s disease, it is important for Molsbury to investigate the relationship between diet and each condition, and how multiple prodromal conditions are associated. Said. of [Parkinson’s].. “

Molsberry and colleagues conducted an analysis of participants in a nurse health survey and a medical professional follow-up survey that collected dietary information from participants every four years since 1986. Within these cohorts, researchers calculated scores for adherence to multiple dietary patterns, including the Alternative Mediterranean Diet and Alternative Healthy Diet Index.

Prodromal symptoms of Parkinson’s disease evaluated in this study include body pain, constipation, possible REM sleep behavior disorder, excessive daytime sleepiness, Color blindness, Hypouria and depressive symptoms.

A total of 47,679 participants were analyzed in this study. Of these, 17,400 completed a 2012 survey on REM sleep and constipation and were included in a subset of patients with five additional prodromal functions evaluated between 2014 and 2015.

Compared to the group with the lowest adherence to alternative Mediterranean diets, Molsberry and colleagues found that the odds ratio for experiencing more than two features was 0.82 (95% CI, 0.68-1.0), 0.67 at baseline. (95% CI, 0.54-0.83) Adherence to long-term diet.

They found similar results in association with adherence to the alternative health feeding index. The researchers also observed a similar pattern when comparing the occurrence of two and one prodromal with a zero prodromal, but the pattern diminished as the pattern decreased.

In a study of specific prodromal features and dietary patterns, Molsbury and colleagues found that long-term adherence to an alternative Mediterranean diet was associated with constipation, excessive daytime sleepiness, and reduced risk of depressive symptoms. I found that. These results were similar to the Alternative Healthy Eating Index, but the association between long-term dietary compliance and reduced risk of depressive symptoms was slightly important.

Examination of specific elements of another Mediterranean diet found that increased consumption of vegetables, nuts, legumes, and moderate alcohol was associated with a reduced risk of more than two prodromal symptoms ..

“Our study is clinically manifested in not establishing a causal relationship between following a healthy eating pattern and the risk of features of prodromal Parkinson’s disease, and adhering to a healthy eating pattern It is important to note that we do not explore whether we can delay or prevent the onset of Parkinson’s disease, emphasized Molkinberry. “But our research was added to previous literature, Healthy eating pattern May decrease [the] Risk of Parkinson’s disease and prodrome of Parkinson’s disease. “

Physicians suggested that clinical practice should consider encouraging physicians to eat a healthy diet, saying, “This is a healthy diet based on our findings. For example, they are rich in foods such as fruits, vegetables, nuts, and legumes that do not have to have a particular dietary pattern, such as the Mediterranean diet, and have low to moderate intakes of lean meat and processed foods.”

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