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One Targeted Dose of Breast Cancer Radiation Therapy May Be “As Effective as Full Course” According to New Research

 


Friday, August 21, 2020, 1:39 pm

Has been updated Friday, August 21, 2020, 1:39 pm
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In this study, targeted therapy during surgery was found to be as effective as a long course of treatment. (Shutter stock)

The researchers found that giving a single targeted dose of radiation therapy to patients with breast cancer was safe and could be as effective as the entire course of treatment.

Long-term studies have shown that patients treated for a shorter period are less likely to die of other types of cancer or heart disease during the five years following treatment than patients treated with a longer-term treatment plan. I will.

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However, this study has been criticized by cancer experts.

What is targeted therapy?

Developed by a doctor at University College London (UCL), Targeted Intraoperative Radiation Therapy (TARGIT-IORT) treats patients with a single, targeted radiation dose that targets the interior of the breast. It only occurs after the tumor has been surgically removed.

This treatment is placed directly on the cancer in the breast and is administered using a small device that allows the patient to receive radiation therapy at the same time as the surgery.

People receiving regular radiation therapy may face 15 to 30 visits. However, those elected to TARGIT-IORT do not need to return for further treatment.

What was included in the study?

The first studies were conducted in 10 countries between 2000 and 2012. A total of 2,298 women with breast cancer were treated with either targeted therapy and surgery or a regular course of radiation therapy.

Ten years later, the trial found that intraoperative targeted therapy was as effective as a long course of treatment.

The latest trial, half this time, followed women with post-treatment breast cancer for a total of 5 years.

What did your recent research find?

Researchers working on this recent study have announced that the findings support the first conclusion-intraoperative targeted therapy was as effective as long-term treatment.

The study also found that fewer women in the single-treatment group died of other causes such as heart disease, other cancers, and lung problems after treatment.

What criticism did the study face?

However, although the findings may seem promising, Joan Havilland of the Cancer Institute criticized the study because he omitted recognizing improvements in conventional radiation therapy treatment.

“Because of the very low cost for the NHS, a significantly improved patient experience, a very high level of clinical cure, a shorter treatment schedule and smaller breast treatments, we have been using traditional radiation since the TARGIT-A trial design. The therapy has evolved significantly,” she said. ..

Is TARGIT-IORT available on NHS?

Although targeted treatments are currently available at the NHS, few clinics have the necessary equipment.

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