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Coronavirus Vaccine Experts: Watch Out For Dangerous Safety Shortcuts | Nationwide


The country that produces the first practical vaccine in the world gains “soft power”. China is providing the military with an vaccine in the first competition. Russian President Vladimir Putin recently announced that a rapidly progressing vaccine is ready for widespread use.

President Donald Trump said he was “optimistic” when the vaccine was prepared on election day.

But experts say vaccine shortcuts for testing safety and efficacy of vaccines endanger millions of lives in the short-term and undermine public confidence in vaccines and science for the long term, first of all. Coming will warn you of a dangerous rush to reach the final line.

In an interview hosted by the National Press Foundation, vaccine authorities answered questions about US strategy.

Q: Who is the US representative? What are our plans?

A: Distribution is currently being coordinated through the “Operation Warp Speed”, specifically the US Department of Defense.

They were pretty quiet about how they planned this… warp speed is, in many ways, a “black box”… it’s like the Pentagon spirit. Please tell me a lot.

I hope this is a bit more transparent to the process… but they fear this kind of security issue. Cyber ​​attacks and physical attacks, they often talk about it.

It’s actually a good thing to have them announce their plans and be able to coordinate with the states, local governments and districts on how to achieve that, as it will be the Tour Force to make it happen. Would be Much more difficult than providing a mask, PPE, contact trace, or test. This will be the most difficult.

— Dr. Paul A. Offit, Head of Infectious Diseases at the Children’s Hospital of Philadelphia and co-inventor of the rotavirus vaccine

Q: Will the vaccine be prepared by the election date?

A: Some of us are really worried about what a few of these people call us “October Surprise”.

So the problem with operational warp speed is that some vaccines are given tens of millions of times. It’s a large fascinating pool of vaccines that the government can soak in.

From the end of October to early November, I think it is very unlikely that clear evidence will be obtained from Phase 3 efficacy studies. Nevertheless, President Trump said he was fully expecting the vaccine to be available by election day.

The government was enthusiastic about warp speed, pulling out a few vaccines and saying, “We’ve tested these on thousands of people. Seems safe. The immune response is great. I think people are dying. , And we need to get this vaccine out there.”

I think it’s a mistake. Because of the credibility of the vulnerable vaccine in this country, we need to make sure that we have clear efficacy data before launching this vaccine.

You have only one chance to make a first impression. These vaccines are important. I think it’s our way forward between vaccines, immunity, and hygiene. You can’t shake your confidence in the vaccine.

Q: Is there a possibility that the supply will be insufficient?

A: Syringes are probably less of an issue. But vials and stoppers… if I wanted to pay attention to what went wrong, that would be it.

— Dr. Georges Benjamin, Director of the American Public Health Association

Q: What percentage of Americans need to be vaccinated to fight COVID-19?

A: It depends on two things: transmission and vaccine efficacy.

Let’s assume that the infection rate is 2, as many experts do. That is, every sick person infects two people.

Also assume that the efficacy of the vaccine is 75%. (The FDA says it accepts 50% effectiveness.)

To stop the spread, about two-thirds of the American population needs to be vaccinated.

Q: How many doses do I need to give?

A: If you vaccinate one-third of Americans, you get 122 million. Using the twice-inoculated vaccine will result in 240 million people. Whatever it is, it is a particularly complex biological product. It is also a logistically difficult goal.

“Then, you have to put it out there. So you have to be able to distribute the vaccine in far more places than just doctors’ offices and pharmacies. You will have many points of care. Put large doses of vaccine and efficiently inoculate the right people, and one month later with an additional vaccine.

Q: Is there a problem?

A: Adverse events occur when the vaccine is actually administered on a scale of millions (as is this vaccine and all routinely recommended vaccines). (However) there are systems currently in place to actually detect these rare adverse events.

— Dr. Julie Morita, Former Director of the Chicago Woods Department of Public Health, Robert Wood Johnson Foundation

Q: Which vaccine looks best now?

A: I want to defeat it firmly. I haven’t guessed about this anymore. Let’s see what the data looks like.

You are in Phase 1. We really don’t know I am trying to read tea leaves. I’m open to any of these approaches, or many of them, working…I’m not spending anything.

Q: Do you have multiple vaccines? What if they all work?

A: We need multiple winners here. Vaccines are needed for 7 billion people on this planet. No manufacturer can scale to make a sufficient dose.

I hope all goes well. And over time you will see which one works better in your particular situation, but hope there are many winners here.

— Dr. Leonard Friedland, Director of GSK Vaccine, Science and Public Health

(C) 2020 The Mercury News (San Jose, CA)

Distributed by Tribune Content Agency, LLC.

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Copyright 2020 Tribune Content Agency.


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