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COVID-19 symptoms may be less severe in women than in men, which is why-more lifestyle

 


Scientists have found possible explanations for the more severe symptoms and worse outcomes of COVID-19, regardless of age, for why men are at higher risk than women.

Researchers at the Wake Forest Baptist Medical Center in the United States point out the role of the female hormone estrogen in lowering levels of cardiac angiotensin-converting enzyme 2 (ACE2), which may regulate the severity of COVID-19 in women. Did.

Published in the journal Current Hightension Reports, this study reviewed preclinical data on sex-specific hormonal activity, especially estrogen.

“I know that coronaviruses affect the heart and that estrogen is protective against cardiovascular disease in women, so the most likely explanation is hormonal differences between genders. “There seemed to be one,” said Wake Forest School of Medicine, Professor Leanne Groban, lead author of the review.

Researchers found that ACE2, which is attached to the cell membranes of the heart, arteries, kidneys, and intestines, is the coronavirus’s cell receptor responsible for COVID-19 infection, and that it carries the virus to those cells. He said he showed to help the organ system.

The review also pointed out that estrogen reduces cardiac ACE2 levels, which may regulate the severity of COVID-19 in women.

Conversely, higher levels of ACE2 in the organization could explain why women are worse off than men, Groban said.

“We hope our review of the role of estrogen-like hormones in the expression and regulation of ACE2 will explain the gender differences in COVID-19 infection and outcome and will guide current therapies and the development of new therapies. “Groban said.

(This article has been published from the telegraph agency feed without any changes to the text. Only the headings have changed.)

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