When will the Covid-19 vaccine be manufactured in the UK? Latest updates from around the world

The results, led by the National Institutes of Health, have not been peer-reviewed or published, but Professor Robin Shattock, Professor of Mucosal Infections and Immunology at London Imperial College, called the initial results “encouragement.”

“This is a promising start, but efficacy data will be key and will continue to be able to scale in ways that provide global access if this vaccine is successful.”

US President Donald Trump said Mass production begins in the US All vaccines developed before full approval will be rubber stamped for immediate distribution.

But the president accused the US Food and Drug Administration of preventing drug companies from finding people to test the coronavirus vaccine. Trump suggested FDA “deep” element wanted to postpone vaccine until post-election..

It was also reported GSK and Sanofi partner We plan to develop a coronavirus drug and prepare a vaccine for testing by the end of 2020.

Germany announced it €300 million (£269 million) invested in a private biotechnology company At the brink of clinical trials of coronavirus vaccines.

The purchase of 23 percent stake in CureVac caused political backlash in Berlin after the Trump administration reported the attempt to send the company to court and secure a future vaccine supply. In March, CureVac refused to claim that it had been offered to buy the company or its technology.

Good early results for Chinese pharmaceutical companies

June 17, Chinese pharmaceutical company announced positive early results 100% of those vaccinated claim to have elicited an immune response.

The vaccine is developed by the company China National Biotech Group (CNBG), Best candidate out of over 200 other candidates In the race to develop effective vaccination against the disease.

Chinese biotechnology, SinovacHe also said he would like to move to a larger Phase 3 trial in Brazil and announced favorable results for the coronavirus vaccine.

Participation in Africa’s first Covid-19 vaccine trial began on June 24, when volunteers received an injection developed at Oxford University. On the other hand, the continent of 1.3 billion people cannot be left behind.

Large trial Conducted in South Africa, United Kingdom and Brazil..

Other treatments under study

Alongside vaccine development, doctors Testing existing drugs Ebola, malaria, HIV and other viruses. Initial results appear promising, but doctors cannot be certain that the drug will be effective until a complete clinical trial is completed.

of Oxford University-led hydroxychloroquine testOriginally a treatment for malaria, Health Secretary Matt Hancock was welcomed in April as a “major milestone” in the fight against Covid-19.

However, the results of an international WHO survey show that it increases the likelihood of death in hospitalized patients by 9-21%.

Organization Suspended trial on May 25, Citing safety concerns. However, on May 26, leaders of the Oxford-led recovery trials running at the NHS hospital said they would continue based on their data showing no increased risk.

AstraZeneca has initiated Phase 1 clinical trials of the drug AZD7442, which combines two monoclonal antibodies for the prevention and treatment of Covid-19. The trial, funded by the US government, includes up to 48 healthy UK participants aged 18 to 55.

The combination of so-called monoclonal antibodies works by mimicking the body’s natural antibodies.

Breakthrough in dexamethasone

The world’s first coronavirus treatment that significantly reduces the risk of death is given to the following NHS patients: Breakthrough test by British scientists..

A breakthrough event described by Prime Minister Boris Johnson as “a noteworthy achievement”, the common steroid dexamethasone was shown to radically improve the survival potential of the most ill patients. It was

On June 16, Johnson praised the result as the “greatest breakthrough to date” in the treatment of coronaviruses, both in the UK and around the world.

The government has been stocking dexamethasone since March in case the trial is successful. Already supplied to 200,000 patients, it is enough to deal with the second wave of the virus.

Drugs-arthritis, severe allergies and asthma – The entire course of treatment costs only £5 and is expected to have a major impact on the pandemic.

Oxford University scientists, Carry out a trial Since March, it has been announced that for many drugs, a 10-day dexamethasone course reduces the risk of death in ventilator wearers by a third.

The researchers said the drug should be the standard of care for the most ill patients.

UK Vaccine Task Force

April 17, the government Launched task force -Installed under the Bureau of Business, Education and Industrial Strategy (BEIS)-Designed for “quickly develop coronavirus vaccines” to increase production and speed mass production.

Led by Sir Patrick Valence and Deputy Assistant Vice-President Jonathan Phantam, members include pharmaceutical companies such as AstraZeneca and the Welcome Trust.

The government initially invested £14 million into 21 coronavirus research projects, including those by scientists at Oxford University and Imperial College London. On April 21, the funding was further increased with the announcement of an additional £44.5 million for the Oxford and Imperial trials.

A few weeks later, business secretary Arok Sharma announced another £84m in new money to “accelerate his work.”

“The new money will help mass-produce the Oxford vaccine, so if the current trials are successful, people in the UK can be immediately vaccinated.”

To support the UK’s mass production of vaccines, Sharma announced that the UK’s first Vaccine Manufacturing Innovation Center will open one year ahead of schedule in the summer of 2021.

“Last month, the government announced it would accelerate the construction of the UK’s first vaccine manufacturing innovation center based in Harwell, Oxfordshire to further support domestic manufacturing capacity.

“And today we can announce that we will invest another £93m in the center to ensure it opens 12 months ahead of schedule in the summer of 2021.” there is. Sufficient vaccine dose to service the entire UK population in just 6 months. “

How long does it take to make a vaccine and why?