Health
Research says blood pressure drugs do not increase the risk of cancer
There is no evidence that drugs that lower blood pressure increase the risk of cancer, scientists claim to have conducted the largest amount of research on topics that have been discussed so far.
This study should address the “ongoing controversy” and possible link to the onset of cancer about such medications, known as antihypertensive drugs, and reassure people about their safety. The author said.
Emma Copland, an epidemiologist at Oxford University, said the discovery was “most important” because of the known benefits of these drugs in protecting against heart attacks and strokes.
The study, published at the European College of Cardiology, was the largest study of cancer outcomes among participants in randomized trials investigating antihypertensive drugs, according to researchers. Is intended for.
Researchers in all trials were asked for information about which participants developed cancer, and the people behind the study didn’t publish much information to date, so this analysis is still the most detailed. I said.
Researchers are investigating the effects of five antihypertensive drugs, angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta blockers, calcium channel blockers (CCBs), and diuretics Estimated risk of developing cancer. Death from cancer and the development of breast, colorectal, lung, prostate and skin cancers.
They also looked at differences due to age, sex, size, smoking status, and previous use of antihypertensive drugs.
With an average of about 15,000 new diagnoses of cancer over four years, researchers found no evidence that use of the antihypertensive drug class increased cancer risk, regardless of various factors such as age. He said the findings were consistent.
Scientists also said there was no evidence that any type of antihypertensive drug affected the likelihood of developing breast, colorectal, lung, prostate, or skin cancers.
They added that there was no indication that the longer the drug was taken, the greater the risk of cancer, and participants were followed through the course of each trial.
Coland says: “Our results should reassure the public about the safety of antihypertensive drugs against cancer. This is most important given the proven benefits of protecting against heart attacks and strokes.
“Our research addressed an ongoing controversy over whether antihypertensive drugs increase the risk of developing cancer.
“To date, we have used the greatest individual-level, randomized evidence for antihypertensive drugs and provide evidence for the safety of antihypertensive drugs associated with cancer.”
Professor James Raper, Deputy Director of Medicine at the British Heart Foundation, said: “This very large study demonstrates that blood pressure lowering drugs that help prevent heart attacks and strokes do not increase the risk of developing cancer.
“This study further ensures that their use is safe. It is important that patients continue to take blood pressure medications as prescribed to protect their heart and blood vessels.”
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