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Experts say risk of diabetes is more affected by overweight than genetics-Clinical Daily

 


Overweight is a much stronger risk factor for developing type 2 diabetes than genetics, according to a new study. Researchers say that lowering body weight below individual “trigger” thresholds can prevent or even reverse the disease.

Data from more than 440,000 adult participants in the UK Biobank study were grouped according to the genetic risk of diabetes and the body mass index (measurement of weight to height). The group with the highest BMI had an 11-fold increased risk of diabetes compared to participants in the group with the lowest BMI. The highest BMI group was more likely to develop diabetes than all other BMI groups, regardless of genetic risk.

In addition, researchers found that being overweight for a longer period did not affect risk. The results suggest that above a certain BMI threshold, the chances of developing diabetes are high, and individuals remain overweight even when overweight, according to an epidemiologist at the University of Cambridge in England. Brian Milan, Italy.

“The findings show that keeping BMI below the cutoff that triggers abnormal blood sugar levels can avoid most diabetic cases,” Ference said. “This means that both BMI and blood sugar levels need to be regularly evaluated to prevent diabetes. When a person begins to develop blood sugar problems, they try to lose weight. It’s important,” he concludes.

The study was presented at the 2020 European Heart Association conference, published Monday.

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