Health
Researchers at UT are trying to find out why more and more young people have colorectal cancer-Entertainment & Life-Austin 360
Last weekend there was a big question about the news that actor Chadwick Bohsman died of colorectal cancer at the age of 43. Why did someone who looked so good at “Black Panther” live with colorectal cancer for four years?
It shattered the idea that colon cancer is cancer in the elderly. You may even have questioned why historically the first colonoscopies were not recommended until age 50.
Dr. Anna Capasso, an associate professor at the University of Texas Austin Dell Medical School and an oncologist at Livestrong Cancer Institutes, treats and studies lung cancer, breast cancer, and prostate cancer, followed by colon cancer as the most common cause of cancer. .. Deaths in the US, according to Centers for Disease Control and Prevention.
One of the mysteries she and other researchers are trying to solve is why there is an increase in early-onset colorectal cancer (typically seen in people between the ages of 18 and 36) and early-onset colorectal cancer. That is why the cancer seems unresponsive. Current medications and colorectal cancer found in the elderly.
Although the incidence of colorectal cancer over the age of 60 is declining, Kapaso says that the incidence of colorectal cancer in younger people is increasing. Perhaps it’s access to screening, she can identify precancerous lesions and eliminate them. More physician groups, including the American Society of Clinical Oncologists, recommend and encourage screening to begin at age 45 rather than age 50.
People with a family history are advised to start screening 10 years before the age at which the family is diagnosed.
Screening usually means colonoscopy, but for those who do not have known risk factors, it is a stool specimen test, followed by colonoscopy if necessary.
Researchers are also trying to understand why African Americans have more colorectal cancer incidents. According to the CDC, the percentage of African Americans is 40.4 per 100,000, compared to 30.4 per 100,000 Caucasians, 32.5 for Hispanics, 28.5 for Asians, and 29.0 for American Indians.
Unlike other cancers, it has less of a link to genetics. According to Kapaso, 5% of new cases have a confirmed genetic syndrome and only about 10% have a family history.
Capasso says it’s associated with risk factors such as eating a high-fat diet, being overweight, smoking, drinking alcohol regularly, not being active, but having an active lifestyle and smoking Not young patients or regular drinkers, vegetarian or vegan.
“That’s why it’s so hard to understand why and why,” says Kapaso.
To understand what’s happening, a lot of research has been done, especially in early-onset cases, looking for differences in tumor markers and gene mutations between young and older colon patients. I will.
They have not found anything “Something else is happening,” she says.
Last year, researchers at the Dell Medical School investigated whether there were differences in colon incidence between urban and rural populations, but there was no statistical difference.
Kapaso is currently using the tumor cells of the patients she treats to sequence the tumor genes and see how the tumors respond to different treatments.
Capasso hopes that there will be a consortium of shared data to help researchers like other cancers and diseases.
“If we want to make a difference, we have to participate in our efforts and energy,” she says.
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