Health
Inexpensive steroids can save lives of COVID-19 patients with serious illness
The progress was great news, but these discoveries created challenges for Angus and other researchers doing their own research on steroids in COVID-19 patients. I felt it was no longer appropriate to give steroids to some people and placebo to others.
“These findings were so impressive that we had this feeling among clinicians participating in other clinical trials, essentially overnight. [that] …We have to stop trying. “
Therefore, all of these studies ended prematurely. Researchers from three research groups have published the findings collected in the journal JAMA.. One group From France,One is From Brazil, And the third International team Includes Angus of the University of Pittsburgh.
Taken together, the publications of these studies “represent a significant step in the treatment of COVID-19 patients,” Drs. Harry Prescott and Todd Rice Wrote in JAMA editorial.. The results not only further support the use of dexamethasone, but also support the use of another widely used steroid, hydrocortisone.
“I think it’s good news that there are strong and clear indications of the types of treatments that are widely available and inexpensive,” says Angus. He also contrasts these studies with many other studies on COVID-19. Many other studies, including many advertised antimalarial studies, did not randomize participants or include comparison groups. Such measures- Randomized controlled trial — The gold standard for medical research.
“It’s encouraging to be able to successfully and quickly run randomized trials in the face of a pandemic,” says Angus.
Based on these new results and relevant analysis, the World Health Organization on Wednesday Updated guidelines steroid. It is currently recommended for patients with severe or severe COVID-19, such as those who are on a ventilator, but not for patients with mild disease.
You can contact NPR Science correspondent Richard Harris [email protected].
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