Covid-19’s “serious long-term effects” could improve over time, early evidence suggests

“The bad news is that people show COVID-lung disorders 19 weeks after discharge. The good news is that disorders tend to improve over time. It has a mechanism by which the lungs repair themselves. “I am saying that,” said Dr. Sabina Sahanick, a doctoral student at a university clinic in Innsbruck, Austria, who was involved in one of the reports in a clinical news release.

So far, only new research summaries have been published, and the findings are preliminary, but shed new light on the long-term effects of Covid-19.

Sahanic research Data from 86 severe Covid-19 patients enrolled in the study from April to June were included. At a news conference on Friday, Sahanick said the patients were evaluated 6 weeks after discharge and then again 12 weeks later.

Each assessment includes lab tests, lab tests, lung function analysis, chest CT scans, and echocardiography of the heart, Sahanick said. The survey continues with a third assessment at week 24.

Six weeks later, Sahanic of Austria and her colleagues found that 65.9% of patients had persistent Covid-19 symptoms, with shortness of breath and cough being the most common.

“Approximately 50% of our study population showed persistent shortness of breath six weeks after discharge, improving slightly until the second visit,” Sahanic said. Regarding CT findings, we found that about 88% of our study population still showed pathological findings on the first visit and improved to 56% on the second visit.”

The researchers also pointed out in their research summary that some patients had left ventricular diastolic dysfunction in the heart. This refers to an inability of the ventricles to reach their normal volume and abnormal lung function.

“Covid-19 survivors have had persistent lung dysfunction for weeks after recovery, but with modest improvements over time,” Sahanic said. “Therefore, structured follow-up of Covid-19 survivors should be considered.”

These preliminary findings are presented only and are not published in peer-reviewed journals. There are also limitations, such as a small sample of patients and many study participants smoking. Further research is needed to determine if similar findings will appear in a larger and more diverse patient group.

Road to recovery

Another study, presented at an international conference of the European Respiratory Society on Friday, found that 19 patients with severe Covid-19 undergoing pulmonary rehabilitation early in the recovery process had lung volume, balance, muscle strength, We have found that it is associated with improvement in fatigue and certain risk factors of depression and anxiety.

French-based researchers say that patients who “have reduced bedtime” between intensive care and pulmonary rehabilitation have recovered faster. Wrote in their research summary..

However, the ability to walk did not appear to fully recover, so further rehabilitation may be needed and the symptoms of post-traumatic stress disorder with Covid-19 do not appear to have improved.

“At the psychological level, some patients had severe post-traumatic stress disorder after intubation, but did not improve after rehabilitation,” said Yara, a PhD student at the Dieulefit Santé Clinic in pulmonary rehabilitation in France. Al Chikhanie said the investigation was at a press conference on Friday.

Al Chikhanie said one patient was “suffering from memory and flashback. Every time I thought about intubation and thought of being hospitalized from Covid-19, I felt a nightmare and a rapid heartbeat.” I said. “She remembers nothing but wanting to extubate herself.”

Preliminary findings have some limitations. This includes more research needed to investigate rehabilitation of larger patient groups. Findings are not published in peer-reviewed journals.

Overall, there is anecdotal evidence that many patients have suffered debilitating long-term sequelae of coronavirus since the inception of the COVID-19 pandemic,” said Thierry Tol, President of the European Respiratory Society. Stars, the new study hosted the Friday press conference-said in a news release.

“Dr. Sahanick’s presentation is important because it is one of the first comprehensive prospective follow-ups of these patients, showing the severe and long-term effects of COVID-19 on the lungs and heart. Of the patients in the study, 12 weeks after discharge, the lungs and heart were damaged, and nearly 40% still suffered from shortness of breath.” “Al Chikhanie’s study complements this information and shows how essential it is to start pulmonary rehabilitation as soon as the patient becomes physically capable.”

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