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UK tests whether COVID-19 vaccine is better inhaled and works



Large-scale research on the Imperial and Oxford vaccines is already underway, but this study aims to see if the vaccine is more effective when inhaled.

“There is evidence that giving the flu vaccine through a nasal spray can protect people from the flu and reduce the transmission of the disease,” said Dr. Chris Chiu of the Imperial, who leads the study. He suggested that this might be the case with COVID-19.

“It is important to investigate whether direct airway targeting can provide an effective response compared to a vaccine that is injected into the muscle,” Chiu said in a statement.

The study is currently recruiting participants between the ages of 18 and 55 and hopes to begin vaccination of Londoners in the coming weeks.

Previous studies have shown that vaccines delivered by inhalation require lower doses than injections, which may help extend the limited supply.

“A group has the right vaccine, but the delivery method may be wrong, and only such trials can tell,” said Robin Chatok, head of vaccine development at Imperial. Stated.

Imperial vaccines use synthetic strands of virus-based genetic code. When injected into the muscle, the cells of the body itself are instructed to make a copy of the pointed protein on the coronavirus. It is expected to elicit an immune response and allow the body to fight future COVID-19 infections.

In comparison, Oxford vaccines use a harmless virus (a chimpanzee cold virus, designed to prevent its spread) to carry the coronavirus spike protein into the body and provoke an immune response.

Oxford temporarily suspended its large-scale vaccination test last week after a UK participant reported severe neurological symptoms. It resumed on Sunday.

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