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Fed “Very Concerned” About Side Effects of AstraZeneca COVID-19 Vaccine



THe is considering whether to comply with UK regulators when the Food and Drug Administration reopens Discontinued coronavirus vaccine trial When a participant suffers a spinal cord injury even though the National Institutes of Health has begun investigating the case.

“The highest levels of NIH are of great concern,” said Dr. Avindra Nath, Intrawall Clinical Director and Leader of Virus Studies at the National Center of Neurology and Neurology, NIH Division. “Everyone wants a vaccine. With major complications, everything can be confusing.”

There remains considerable uncertainty in the frustration of patients who are enthusiastic about advancing vaccine testing as to what happened to unnamed patients. AstraZeneca is conducting a global trial of a vaccine manufactured at Oxford University, and said trial volunteers have recovered from severe inflammation of the spinal cord and are no longer hospitalized.

AstraZeneca has not confirmed that the patient is suffering from transverse myelitis, but Nath and other neurologists said he understood this to be the case. Transversal osteomyelitis causes a series of symptoms with inflammation along the spinal cord that can cause pain, muscle weakness, and paralysis. The UK Regulatory Authority, the Pharmaceuticals and Medical Products Regulatory Agency, has considered the matter and has allowed the resumption of trials in the United Kingdom.

The last thing you want to do is hurt a healthy person.

— — Dr. Avindra Nath, NIH

AstraZeneca “Necessary[s] Nath said: “I want to see how we can help, but it’s difficult to do because of the lack of information.”

Trials are difficult because it is difficult to assess the cause of rare injuries that occur during a vaccine trial, and scientists and authorities need to weigh the risks of unusual side effects for vaccines that may suppress pandemics. The decision as to whether to continue is complicated.

“There are so many factors involved in these decisions,” said Nath. “I’m sure everything is ready. The last thing you want to do is hurt a healthy person.”

NAS said the NIH has not yet obtained tissue or blood samples from patients in the United Kingdom and the study is in the “planning stage.” Scientists in the United States can look at samples of other vaccinated patients to see if any of the antibodies produced in response to the coronavirus attack the brain or spinal cord tissue.

He said such a study could take a month or two. The FDA declined to comment on the time it will take to decide whether to move forward.


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