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Scientists say the old bat virus may be the backbone, reviving the “laboratory origin theory”-Indian news
The Sars-Cov-2 virus, which causes Covid-19, shows signs that are uncommon in naturally evolved pathogens, and a group of researchers rekindled the theory that the virus may have been developed in the lab. – Scientist concepts and public health officials rejected on several occasions.
The allegations were made in a paper uploaded by Li-Meng Yan, who specializes in virology and immunology at the Hong Kong Public Health School, before moving to the United States, where she appears to be seeking evacuation.
“SARS-CoV-2 exhibits biological properties that are inconsistent with naturally occurring zoonotic viruses. This report describes genomic, structural, medical, and literature evidence. Together. It strongly contradicts the theory of natural origin, “says the paper, but has not yet been reviewed.
The theory of natural origin was first reported by Nature Medicine in a March 17 paper. Researchers said the virus has 96% similarity to a coronavirus called RaTG13 found in bats.
Yang and her colleagues are increasingly suspicious of the natural existence of this bat coronavirus, and instead, Sars-Cov-2 has a strong overlap with the other two bat coronaviruses, ZC45 and ZXC211. Claims.
“Evidence shows that SARS-CoV-2 is a laboratory product created using the bat coronavirus ZC45 and ZXC21 as templates and backbones,” the report states.
Researchers have added three hypotheses to support their claim that the virus may have been produced in the laboratory: “This is the material that SARS-CoV-2 can use in the laboratory. It’s also a demonstration of how to use wells to create things quickly and conveniently-a documented technique. “
The first of these is the history of the coronaviruses ZC45 and ZXC21, both discovered by the Military Research Institute-one at the Third Military Medical College (Chongqing, China) and the other at Nanjing Command Medicine. Laboratory (Nanjing, China).
The second involves a component of the virus called the receptor binding motif (RBM) within the spike protein, the portion of the virus that hooks into the target cell. The RBM “similar to that of SARS-CoV from the 2003 epidemic in a questionable way. Genomic evidence suggests that RBM is genetically engineered,” they said.
The third is related to another function of the spike protein called Flynn cleavage, which was established to “significantly increase viral infectivity and cell affinity”. “This cleavage site is completely absent from this particular class of coronavirus found in nature. In addition, the rare codon associated with this additional sequence is that this furin cleavage site is a product of natural evolution. Rather, it suggests that it is likely to have been artificially inserted into the SARS-CoV-2 genome by means other than simple continuous passage or mulch-co-infected tissue cultures or pairs in animals. The distortion of the replacement event, “they said.
Scientists have not yet commented on these claims in their dissertation.
In an interview at a British talk show earlier this week, Yang claimed that there was concealment of the origin of the virus. “I decided to report this progress to my boss, who is also a World Health Organization (WHO) consultant. There was no response from WHO and my boss. Warned that no one would cross the right line and stay silent. Did.
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