Health
COVID-19 may damage immune cells in the bone marrow
September 23, 2020-Coronavirus can damage bone marrow cells in patients with severe COVID-19, New research Published in the journal Scientific immunochemistry..
Previous studies have shown that COVID-19 produces an “exaggerated” response from the immune system, and in some patients this can occur in immune cells in the bone marrow, researchers say. Is writing.
The findings “support the idea that therapeutic strategies that target the release of cells from the bone marrow should be considered in this disease,” they wrote.
of The research team analyzed the immune profile Of 43 patients hospitalized during the peak of the British pandemic. They have discovered several changes in the immune signature, especially monocytes, which are new immune cells released from the bone marrow into the bloodstream.
In most patients with mild COVID-19, abnormal levels returned to normal during hospitalization. However, in more severe COVID-19 patients, monocytes did not function properly.
Researchers did not know if the monocytes changed before they were released from the bone marrow or after they entered the blood. To reuters..
Nonetheless, treatments that block the release of monocytes may reduce the exaggerated immune response associated with severe COVID-19, the news service reported.
Importantly, the researchers wrote that the presence of immunological disorders before the patient received intensive care meant that the hospital should start immunotherapy immediately after admission.
“Treatment of patients early after hospitalization may be most beneficial, but it destroys immune function,” they wrote.
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