Health
Non-raw carrots can cause allergic reactions-more lifestyles
Contrary to the idea that raw carrots cause allergic reactions, cooked carrots can also have this effect, a study conducted by a research team at Bayreuth University suggests.
The carrot allergen Dau c 1 has a structure that is harmless to allergic patients even when heated very much.
However, as soon as the temperature drops, it greatly returns to its natural structure. Researchers publish their research in the journal Molecular Nutrition and Food Research.
“Our findings clearly suggest that patients sensitive to carrot allergens should generally avoid eating carrots. Heating carrots can also cause an allergic reaction. Some protein structures are not or only incompletely destroyed, “said Professor Birgita Wohrl of the Biochemistry IV research group at the University of Bireut.
“The risk of allergic reactions in allergic patients is not limited to eating freshly cooked or canned carrots, but also when carrot extracts are added to foods,” said the first author of the study. , Tessa Jacob M.Sc., A PhD student in the Biochemistry IV Research Group, added.
The natural carrot allergen Dau c 1 is actually a mixture of several proteins that are structurally very similar. These so-called isoallergens were produced individually in the laboratory by bacteria. Both natural Dau c 1 and protein mixtures of individual isoallergens were examined at temperatures up to 95 degrees Celsius to see how their structure changed as the temperature increased or decreased.
This analysis showed that natural mixtures and almost all isoallergens can cause allergies even after cooling to 25 degrees Celsius. Despite previous heating, antibodies present in the organism of allergic patients still cause an allergic reaction. In some cases, this effect is less pronounced than before heating, but is usually maintained.
“This is the first time the Dau c 1 isoallergen has undergone such an extensive set of tests. Tessa Jacob M.Sc is working to identify which allergen triggers an immune response under the conditions tested. It was especially important to individually test for structurally similar molecules.
Tests have shown that the structural stability of carrot allergens does not depend solely on temperature. The acidity expressed by the pH value is also important. Of particular interest is the pH value of 3. It is usually predominant in the stomach after food intake.
At this level of acidity and normal room temperature, at least some epitopes may continue to be present despite previous heating. Epitopes are molecular structures that cause the immune system of allergic patients to recognize each allergen and cause an allergic reaction.
Researchers used magnetic resonance spectroscopy (NMR) and CD spectroscopy primarily at the Bayreut Campus laboratory to investigate the structure of the Dauc 1 isoallergen. Other analytical procedures were supported by the Paul Ehrlich Institute in Langen and Nanotemper Technologies in Munich.
(This article is published from the telegraph agency feed without any changes to the text. Only the headline has changed.)
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