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China Promotes Emergency Use of COVID Vaccine Despite Concerns – NBC Los Angeles

 


After the first shot, he didn’t react. However, Kan Chai was disappointed with the second dose of COVID-19 vaccine, which was approved for emergency use in China.

“When I was on the road, I suddenly felt dizzy as if I was drunk,” a popular writer and columnist told a webinar earlier this month. After a while, I felt better. “

He is a rare explanation from hundreds of thousands of people who have been vaccinated with China before the final regulatory approval for general use. This is a rare move that raises ethical and safety issues, as companies and governments around the world are competing to develop vaccines to stop the spread of the coronavirus.

Chinese companies have previously gained attention by vaccination of top executives and key researchers before human experimentation to test safety and efficacy begins. Over the last few months, the emergency use designation approved in June has infused a much higher number, and that number is expected to increase.

Chinese health officials said on Friday that most of the eradication of the disease needed to be taken to prevent China from recurring. However, one outside expert questioned the need for emergency use if the virus stopped spreading in the country where the virus was first detected.

It is not known exactly who and how many have been injected so far, but Chinese vaccine makers provide some clues. CNBG’s top executives recently announced that CNBG, a subsidiary of state-owned Sinopharm, has provided the vaccine to 350,000 non-clinical trials with approximately 40,000 enrolled people.

Another company, Sinovac Biotech Ltd., injected 90% of its employees and their families, or about 3,000, most of them under emergency provisions, said CEO Yin. Weidong said. It also provided tens of thousands of rounds of its corona bag to the Beijing Municipal Government.

Separately, the Chinese military has approved the use of a vaccine developed by biopharmacy company CanSino Biologics Inc. for military personnel.

“Emergency use is the first priority for vaccine researchers and vaccine manufacturers, because in the event of a pandemic, when these people become infected, there is no way to produce a vaccine,” Yin said. ..

Currently, large Chinese companies, including major telecommunications company Huawei and broadcaster Phoenix TV, have announced that they are working with Sinopharm to obtain vaccines for their employees.

Some people who say they work for “front-line” organizations said on social media that their workplace offers vaccinations of about 1,000 yuan ($ 150). They declined to comment, stating that they would need permission from their organization.

In established but limited practice, drug therapies have historically been approved for use during the third and final stages of human trials. Chinese companies have four vaccines in Phase 3 — two from Sinopharm and one from Sinovac and CanSino.

The Chinese government has referred to the World Health Organization’s Emergency Use Principles to develop the World Health Organization’s Emergency Use Principles through a rigorous process, National Health Commission official Chung Zhongwei said at a press conference on Friday.

He said there were no serious side effects in clinical trials.

“We have made it very clear that the COVID-19 vaccine we used urgently is safe,” Zheng said. “We can ensure their safety, but their effectiveness has not yet been determined.”

Under urgent rules, he said, priority access was given to high-risk personnel such as medical and customs workers and those who had to work abroad. He refused to provide the exact number.

“In the case of China, the pressure to prevent imported infections and domestic resurgence remains enormous,” Chung said.

However, Diego Silva, a bioethics instructor at the University of Sydney, said that vaccination of hundreds of thousands of people outside of clinical trials is currently rare in the country and has few arrivals in China. Centrally isolated, stating that there is no “scientific benefit”.

“If you’re in the United States where the virus is still rampant, it’s a little different, but in a country like China it doesn’t seem to make sense to me,” he said. “In China, there aren’t enough viruses in China to guess something, so we’re introducing many other factors by injecting people out of the test.”

Chung said that everything injected under emergency use is being closely tracked for adverse health effects.

Columnist Kan Chai wrote in an article posted online in September that he decided to register after hearing that a state-owned company was looking for volunteers, despite his initial hesitation.

He didn’t say if he was in case of emergency use, but the timing of his preventive contact suggests it was. He took his first dose in late July, when the emergency vaccination began and the trial was almost over.

“I want to be a little white rat, and the biggest reason is that I have confidence in our country’s vaccination technology,” he said.

His real name is Li Yong, but his 1.65 million followers on social platforms like Twitter, Weibo, know him better with his pseudonym. He declined the interview request.

He explained taking the vaccine at a public webinar hosted by the popular medical media outlet 8am Health Insight. It is unknown why he was eligible to receive it.

Poor information about the scope, size, and scientific benefits of the program is available. CNBG and parent Sinopharm declined to comment. Chung, an employee of the National Health Commission, was unaware of the Kanchay case.

Emergency use may be the right path, but Chinese companies lack transparency on issues such as informed outlets, said Joy Chan, a professor of emerging science ethical governance at the University of Kent in the United Kingdom. Said.

Zhang said he couldn’t find any relevant information on Synofam’s website and said that few other publications were made other than the reports published in the International Medical Journal.

She said relatively much information is publicly available about other exams, such as those conducted by Oxford University and AstraZeneca. The trial was discontinued after participants had serious neurological side effects and resumed only after clinical data were submitted to an independent review board.

China has had various scandals over the last two decades and has been plagued by vaccines.

A recent case was in 2018, when Changsheng Biotechnology Co. tampered with records and was investigated to produce an ineffective rabies vaccine for children.

In 2017, the Wuhan Biopharmaceutical Research Institute, a CNBG subsidiary that supports one of the Phase 3 trial vaccines, found it ineffective to produce a defective diphtheria vaccine.

Public anger at the incident prompted a review of the Vaccine Punishment Act in 2019. The country has increased oversight of vaccine development and distribution processes and increased penalties for producing data.

These concerns seem to be a thing of the past. Guizhen Wu, a biosafety expert at the Centers for Disease Control and Prevention in China, said the vaccine could be provided to the general public in China in November. She said she took the vaccine in April.

An overseas employee of a Chinese state-owned company, who spoke on condition of anonymity because he was not authorized to speak to the media, said he had decided to register last week.

She said she wasn’t worried because vaccines are a government priority, so authorities will keep an eye on the process.

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Wu was reported from Taipei, Taiwan. Associated Press producer Olivia Chan and video journalist Dake Kang contributed to this report.

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