Health
Coronavirus: a 100-year-old vaccine tested as a viral weapon
Dr. Philip Supplies, research director at CNRS, owns original test tubes on March 22 including the French strain Calmette-Guerin-Bacillus.
Photographer: Denis Charlet / AFP via Getty Images
Photographer: Denis Charlet / AFP via Getty Images
Healthcare workers in Melbourne have been vaccinated to see if the vaccine used to prevent tuberculosis is protected from coronavirus.
Calmette-Guerin or BCG shots have been in widespread use for nearly 100 years, and recognition of their unintended benefits has increased. Not only is it an early general immunotherapy Bladder cancerAnd so on Train your bodyIs the first line of immune defense to better fight infection.
World Health Organization knows if BCG vaccine can reduce disease in people infected with coronavirus, given immunization against Covid-19 disease that causes pandemics, especially for more than a year It is important to encourage international groups to cooperate in research led by Nigel Curtis, Chief of Infectious Disease Research, Murdoch Children’s Institute In Melbourne.
“It can boost the immune system, so it can better protect against a wide variety of infections, more generalized methods of different viruses and bacteria,” said Curtis, a professor of childhood infections. Said University of Melbourne Head of the Royal Children’s Hospital Infectious Diseases Division of the city.
Read more: Why Coronavirus Takes More Time for Drugs and Vaccines: QuickTake
Hospital staff who volunteered to participate in a 6-month trial involving 4,000 Australian health care workers are randomly assigned and will be vaccinated against seasonal flu and tuberculosis or only flu from Monday. Will be
In this case, the placebo vaccine will not function as a control. BCG shots usually cause a local skin reaction, leaving scars and defining which group has been vaccinated against TB.
Boston, Netherlands
A similar study Netherlands. Curtis said in a Saturday interview that he was talking with potential trial sites in Boston as well as other Australian cities.
Inexpensive vaccines used to vaccinate about 130 million newborns each year around the world may provide protection for a wider group of people, but the priority is to reduce There are healthcare workers who are at high risk of getting a coronavirus during care.
“We need to consider every conceivable way to protect healthcare workers,” Curtis said. “And there will be a special need to reduce the time our healthcare workers are absent.”
Studies in African infants have shown that BCG vaccines are likely to enhance tuberculosis and other diseases by enhancing the body’s innate immune system, especially leukocytes that target nonspecific pathogens before antibody responses usually begin after a few days. It has been shown to provide protection against pediatric infections.
Blood samples taken at the start and end of the study will show who has been infected with the coronavirus. On the other hand, participants record symptoms during the test. The investigation’s data monitoring committee will review the results after three months and look for signs that the approach is working.
“If we didn’t think this would work, we wouldn’t have done this,” Curtis said. “We can’t guarantee that this will work, and of course, the only way to find it is our trial.”
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