UK coronavirus case surge “could accelerate the progress of the Oxford vaccine trial”

Pfizer’s vaccine is called an mRNA vaccine, which sends genetic material rather than injecting part of the virus directly into the body.

mRNA vaccines are programmed to produce parts of the virus itself by injecting into the body molecules that tell the cells what they build to fight the virus. The immune system then learns how to fight it.

4. Varneva: 60 million

The government has given Valneva, whose vaccine is understood to be in the preclinical stage of development, an undisclosed amount to expand its plant in Livingston, Scotland.

The government announced a dose contract of 60 million doses on July 20, but said the company had in principle agreed with the UK government to provide doses of up to 100 million doses.

Valneva’s jab is an inactivated whole virus vaccine. That is, it injects the damaged version of the coronavirus itself into the body.

Although the virus is destroyed in a way that it cannot cause infection, the body recognizes it as a dangerous intruder and therefore initiates a memorable immune response in the case of a real Covid-19 infection.

5. Janssen (Johnson & Johnson): 30 million

The government has agreed to purchase 30 million doses of the vaccine produced by Janssen if it works.

Authorities have agreed that the company will support the development of jabs by partially funding global clinical trials. Janssen’s first human trial of the jab began in mid-July and is being held in the United States and Belgium for adults over the age of 18.

Jab is a type of jab called Ad26.COV2-S, recombinant, viral vector recombinant vaccine.

Proteins that appear outside the coronavirus are reproduced in the laboratory and injected into the body to stimulate the immune response.

The “Ad” part of the name of the vaccine means that it functions by using adenovirus (the virus best known to cause the common cold) as a means of transporting the genetics of coronavirus into the body. To do.

6. Novavax: 60 million

The UK has ordered 60 million doses of the vaccine being developed by the US-based company Novavax. It will help fund late-stage clinical trials in the UK and also support plans to manufacture vaccines in the UK.

The Novavax jaw, named NVX-CoV2373, showed positive results in early clinical trials.

The immune response occurs in 100% of those who receive it and is said to be safe and “generally well tolerated.”

Novavax candidates are also recombinant vaccines that transport spike proteins outside the coronavirus into the body to elicit the immune system.

7. Imperial College London: Quantity unknown

Scientists at Imperial College London are working on the hopes of Britain’s second-born jab. Candidates are still a major player, although they are slightly behind Oxford’s vaccine in terms of clinical trial progress.

It is understood that the UK government has agreed to purchase the vaccine if it works, but the details of the contract have not yet been released.

Imperial jabs are now in the second stage of human testing, after appearing safe in early testing.

Imperial College London attempts to deliver genetic material (RNA) from the coronavirus, which programs cells in the patient’s body to regenerate spike proteins. Transports RNA inside the droplets injected into the bloodstream.