Health
Studies show a link between sleep apnea and Alzheimer’s disease
Can sleep disorders lead to the most common forms of dementia?
Scientists have long suspected a link between obstructive sleep apnea and Alzheimer’s disease, a memory-sucking illness in patients.
Now they have visual evidence in the brain.
Plaque and tangles are characteristic signs of Alzheimer’s disease. Scientists now have visual evidence that it is also present in some patients with sleep apnea. This is a serious condition that occurs when a person’s breathing is repeatedly interrupted during sleep.
Dr. Smita Patel is a neurologist at the North Shore University Health System.
“In previous research studies, we couldn’t make that link or association directly,” Patel said. “Of course, if you don’t breathe and oxygen, especially if you can’t remember when you wake up, or if you feel tired during the day, it’s likely to have some effect on your brain cells.”
Upon closer examination of the brain tissue of patients with sleep apnea, researchers in Australia and Iceland found that the more severe the sleep apnea, the more amyloid plaques accumulated in the hippocampus. This is the center of memory in the brain. Sleep interruption interrupts important processes in the brain, such as the removal of toxins.
“It should be taken seriously,” Patel said. “Especially if you don’t want to follow the path of having memory problems later in life.”
The authors of the study said that continuous positive airway pressure or CPAP, a common treatment for sleep apnea, did not appear to reduce injury, but doctors said it was an important factor in prevention. I am.
“I think the treatment of sleep apnea with a CPAP machine is still important, especially if you have moderate or severe sleep apnea,” Patel said.
Patients in this study did not show clinical symptoms of dementia before they died, suggesting that they may have been in the early stages before dementia.
“We try to catch you early. We don’t want to wait until we have symptoms like” I can’t remember who my child is “or” Where are you in the house? “,” Patel said. “Therefore, it is not desirable to progress to that extent before starting treatment for sleep apnea.”
There is already evidence that insomnia plays a role in dementia. Researchers want to conduct larger clinical trials of sleep apnea and hope that their findings will ultimately lead to new therapeutic goals that will help prevent Alzheimer’s disease.
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