Health
Description: What is the Cat Que virus? Does it infect humans?
In a study published in the Indian Journal of Medical Research in July, scientists from the Pune-based Largest Containment Institute and the ICMR-National Institute of Virology found antibodies against the Cat Que virus (CQV) in two human serum samples. It points out that it exists.
What do you say about research?
The presence of the Cat Que virus has been reported primarily in Chinese Akai Eka and Vietnamese pigs. The study collected 1020 human serum samples showing acute febrile illness between 2014 and 2017. However, all of these samples were found to be negative for CQV when tested in real-time RT-PCR. Most of these samples (806) were collected from Karnataka, followed by Maharashtra (116), Kerala (51), Madhya Pradesh (20) and Gujarat (27).
However, antibody positivity was recorded in two of the 883 samples tested for antibody presence. These two samples were taken from Karnataka in 2014 and 2017. Importantly, this study showed that the virus was isolated from a Jungle myna serum sample in the Sagar district of Karnataka in 1961. The virus was characterized as CQV in 2016 using next-generation sequencing technology. ..
Why was this study done?
The study, conducted from 2017 to 2018, was conducted to develop a diagnostic test for CQV in the wake of the epidemic of a similar species of red-green algae in India.
What is the Cat Que virus?
In the case of CQV, domestic pigs are considered to be the major mammalian host. Antibodies to the virus have been reported in pigs raised locally in China, indicating that the virus is capable of forming a “natural cycle” locally and spreading through mosquitoes to pigs and other animal populations. I am.
According to a 2015 paper published in Vector Borne and Zoonotic Diseases, CQV belongs to the Simbu serotype and infects both human and economically important livestock varieties. It was first isolated from mosquitoes in 2004 while monitoring arbovirus activity in northern Vietnam. In this study, researchers reported a CQV strain (SC0806) isolated from mosquito samples collected in China in 2006 and 2008.
How can humans become infected and are there any sources of concern?
Humans can also be infected with mosquitoes. In this study, scientists note that due to the positiveness of human serum samples and the ability of mosquitoes to replicate CQV, there is only a “potential disease-causing” CQV in the Indian scenario. “Vectors, availability of primary mammalian hosts (pigs), and confirmation of CQV from Jungle myna indicate that the orthobunya virus has potential as a public health pathogen in India,” the study said. (CQV belongs to the genus Orthobunyavirus).
So is this virus dangerous?
It’s not clear. Other viruses that belong to the same genus as CQV and are also transmitted through mosquitoes include the Cash Valley virus, which can cause meningitis, the Lacross virus, which can cause childhood encephalitis, and Jamestown Canyon encephalitis. It includes the Jamestown Canyon virus, which can cause it, and the Gualoa virus, which causes Jamestown Canyon encephalitis. Causes febrile illness.
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