Health
Common colds of the past act as protection from COVID-19: research
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(IANS)
In the midst of great progress, researchers have discovered that people who have had a seasonal or cold in the past may be protected from COVID-19.
The study, published in the journal mBio, also suggests that immunity to COVID-19 may last for long periods of time, and in some cases for life.
In this study, SARS-CoV-2, the virus that causes COVID-19, is a long-lived immune cell that detects pathogens, creates antibodies that destroy them, and stores them for the future. It has been shown to induce cells.
The next time the pathogen attempts to enter the body, those memory B cells can act even faster and clear the infection before it begins. Since memory B cells can survive for decades, COVID-19 survivors can be protected for long periods of time from subsequent infections, but further research needs to support this, researchers said. I am.
This study is also the first to report cross-reactivity of memory B cells. In other words, B cells that once attacked the coronavirus that causes the common cold seemed to recognize SARS-CoV-2 as well.
The authors of the study believe that this means that (almost everyone) infected with the common coronavirus may have some pre-existing immunity to COVID-19.
“Looking at blood samples from people recovering from COVID-19, many of them have existing memory B that can recognize SARS-CoV-2 and quickly produce antibodies that can attack it. It appeared to have a pool of cells, said Mark Sungster, principal research author at the University of Rochester in the United States.
The findings are based on a comparison of blood samples from 26 healthy donors who had recovered from mild to moderate COVID-19 and 21 healthy donors whose samples were collected long before exposure to COVID-19. I will. From these samples, the authors of the study measured memory B cell and antibody levels that are present in all coronaviruses and target specific parts of spike proteins that are important to help the virus infect cells. Did.
The Spike protein looks and behaves slightly differently for each coronavirus, but one of its components, the S2 subunit, remains approximately the same for all viruses.
Memory B cells are indistinguishable from different coronavirus spike S2 subunits and attack indiscriminately.
The study found that it applies to two cold-causing viruses and a subclass of betacoronavirus, which includes SARS, MERS, and SARS-CoV-2.
“Now we need to see if this existing pool of memory B cells correlates with milder symptoms and a shorter course of illness, or if it helps increase the effectiveness of the COVID-19 vaccine. There is, “the author writes.
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