Health

Vitamin D deficiency leads to zebrafish obesity and stunting-ScienceDaily

Using the zebrafish model, researchers at North Carolina State University have discovered that early developmental vitamin D deficiency can upset the metabolic balance between growth and fat accumulation. The results suggest an association between vitamin D and metabolic homeostasis or equilibrium.

A research team led by Seth Kulman, a professor of biological sciences at North Carolina State University, found a premature zebrafish diet in one of three diets: no vitamin D (or vitamin D null), vitamin D fortification and management. I examined the group. Zebrafish spent four months on a particular diet, after which researchers examined growth, bone density, triglyceride, lipid, cholesterol, and vitamin D levels. They also investigated important metabolic pathways involved in fat production, storage, mobilization, and growth promotion.

Zebrafish in the vitamin D deficient group averaged 50% smaller than the other two groups and had significantly higher fat accumulation.

“Zebrafish deficient in vitamin D showed both hypertrophy and hyperplasia. Both the size and number of fat cells increased,” says Kullman. “They also had higher triglycerides and cholesterol, which are characteristic of metabolic imbalances that can lead to cardiac metabolic disease, which, coupled with dysgenesis, leads vitamin D to energy growth. It shows that it plays an important role in ability. Fat storage. “

After the first test, vitamin D-deficient zebrafish were fed a vitamin D-rich diet for an additional 6 months to see if the results were reversed. The fish continued to grow and began to utilize their fat reserves, but did not catch up with other cohorts and retained residual fat deposits.

“This study shows that vitamin D deficiency can affect metabolic health by disturbing the normal balance between growth and fat accumulation,” says Kullman. “For some reason, the energy that is supposed to grow is being transferred to the production of fats and lipids, and this development cannot be easily undone. The mechanism is not yet understood, but we do it. I’m starting to make fun of it. “

In future work, it will be necessary to examine the offspring of mothers with vitamin D deficiency to determine if this vitamin deficiency has an inherited epigenetic effect.

Story source:

material Provided by North Carolina State University.. Note: The content can be edited in style and length.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

Pictures Credit